Abstract

This Administrative Core will oversee the coordination of the four component projects of this overallapplication. The core will organize regular working meetings to discuss findings and future directions acrossthe projects. The Core will also organize visits of the External Advisory Committee on alternate years. TheExternal Advisory Committee includes: Drs. Mary-Jeanne Kreek (The Rockefeller University), Peter Kalivas(Medical University of South Carolina) and Marc Caron (Duke University). These advisors have all agreed toserve.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
5P01DA021633-02
Application #
7697590
Study Section
Special Emphasis Panel (ZDA1-RXL-E (30))
Project Start
2008-07-01
Project End
2012-06-30
Budget Start
2008-07-01
Budget End
2009-06-30
Support Year
2
Fiscal Year
2008
Total Cost
$13,963
Indirect Cost

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Mabrouk, Omar S; Han, John L; Wong, Jenny-Marie T et al. (2018) The in Vivo Neurochemical Profile of Selectively Bred High-Responder and Low-Responder Rats Reveals Baseline, Cocaine-Evoked, and Novelty-Evoked Differences in Monoaminergic Systems. ACS Chem Neurosci 9:715-724
García-Fuster, M Julia; Parsegian, Aram; Watson, Stanley J et al. (2017) Adolescent cocaine exposure enhances goal-tracking behavior and impairs hippocampal cell genesis selectively in adult bred low-responder rats. Psychopharmacology (Berl) 234:1293-1305
Burghardt, P R; Krolewski, D M; Dykhuis, K E et al. (2016) Nucleus accumbens cocaine-amphetamine regulated transcript mediates food intake during novelty conflict. Physiol Behav 158:76-84
Rana, Samir; Nam, Hyungwoo; Glover, Matthew E et al. (2016) Protective effects of chronic mild stress during adolescence in the low-novelty responder rat. Stress 19:133-8
Litvin, Yoav; Turner, Cortney A; Rios, Mariel B et al. (2016) Fibroblast growth factor 2 alters the oxytocin receptor in a developmental model of anxiety-like behavior in male rat pups. Horm Behav 86:64-70
Flagel, Shelly B; Chaudhury, Sraboni; Waselus, Maria et al. (2016) Genetic background and epigenetic modifications in the core of the nucleus accumbens predict addiction-like behavior in a rat model. Proc Natl Acad Sci U S A 113:E2861-70
Cohen, Joshua L; Glover, Matthew E; Pugh, Phyllis C et al. (2015) Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci 37:203-14
Glover, M E; Pugh, P C; Jackson, N L et al. (2015) Early-life exposure to the SSRI paroxetine exacerbates depression-like behavior in anxiety/depression-prone rats. Neuroscience 284:775-97
Cohen, Joshua L; Glover, Matthew E; Pugh, Phyllis C et al. (2015) Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci 37:203-14
Chaudhury, Sraboni; Aurbach, Elyse L; Sharma, Vikram et al. (2014) FGF2 is a target and a trigger of epigenetic mechanisms associated with differences in emotionality: partnership with H3K9me3. Proc Natl Acad Sci U S A 111:11834-9

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