Abstract

The Administrative Core will provide administrative oversight of the entire Program Project. This will include not only budgetary and scientific oversight and coordination of individual Projects and the Behavioral Core, but also organization of meetings and interactions with the Scientific Advisory Committee [Drs. Kent Bemdge (University of Michigan), Regina Carelli (University of North Carolina) and Ron See (Medical University of South Carolina)], and coordination with our Statistical Advisor, Dr. Ed Rothman (University of Michigan).

Public Health Relevance

Addiction is a major public health problem in the United States. The goal of this Project is to use a preclinical model to delineate the psychological and neurobiological basis of individual differences in vulnerabilty to develop addiction-like behavior, as this will help identify risk factors that will aid in the development of targeting interventions and treatments.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
5P01DA031656-03
Application #
8638917
Study Section
Special Emphasis Panel (ZRG1-IFCN-H)
Project Start
Project End
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
3
Fiscal Year
2014
Total Cost
$33,549
Indirect Cost
$11,974

  Institution

Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109

  Publications

Ahrens, Allison M; Ferguson, Lindsay M; Robinson, Terry E et al. (2018) Dynamic Encoding of Incentive Salience in the Ventral Pallidum: Dependence on the Form of the Reward Cue. eNeuro 5:
Sarter, Martin; Phillips, Kyra B (2018) The neuroscience of cognitive-motivational styles: Sign- and goal-trackers as animal models. Behav Neurosci 132:1-12
Kawa, Alex B; Robinson, Terry E (2018) Sex differences in incentive-sensitization produced by intermittent access cocaine self-administration. Psychopharmacology (Berl) :
Singer, Bryan F; Fadanelli, Monica; Kawa, Alex B et al. (2018) Are Cocaine-Seeking ""Habits"" Necessary for the Development of Addiction-Like Behavior in Rats? J Neurosci 38:60-73
Mabrouk, Omar S; Han, John L; Wong, Jenny-Marie T et al. (2018) The in Vivo Neurochemical Profile of Selectively Bred High-Responder and Low-Responder Rats Reveals Baseline, Cocaine-Evoked, and Novelty-Evoked Differences in Monoaminergic Systems. ACS Chem Neurosci 9:715-724
Cogan, Elizabeth S; Shapses, Mark A; Robinson, Terry E et al. (2018) Disrupting reconsolidation: memory erasure or blunting of emotional/motivational value? Neuropsychopharmacology :
Turner, Cortney A; Flagel, Shelly B; Blandino Jr, Peter et al. (2017) Utilizing a unique animal model to better understand human temperament. Curr Opin Behav Sci 14:108-114
Pitchers, Kyle K; Wood, Taylor R; Skrzynski, Cari J et al. (2017) The ability for cocaine and cocaine-associated cues to compete for attention. Behav Brain Res 320:302-315
Flagel, Shelly B; Robinson, Terry E (2017) Neurobiological Basis of Individual Variation in Stimulus-Reward Learning. Curr Opin Behav Sci 13:178-185
Koshy Cherian, Ajeesh; Kucinski, Aaron; Pitchers, Kyle et al. (2017) Unresponsive Choline Transporter as a Trait Neuromarker and a Causal Mediator of Bottom-Up Attentional Biases. J Neurosci 37:2947-2959

Showing the most recent 10 out of 48 publications