Abstract

A. Study of the Pathology of Craniofacial Microsomia The purpose of this project is to characterize the 3D skeletal and soft tissue anatomy of patients with hemicranial facial microsomia. Data will be obtained from CT scans of about 50 unoperated patients who are at least 5 years of age. The CT data will be reconstructed to 3D forms by a CEMAX-1000 computer system which can selectively display tissues as well as measure distances and volumes. B. Study of Intracranial Volume Changes after Frontal Bone Advancement The purpose of this project is to quantify the changes in volume of intracranial capacity, brain, and the ventricular system, following frontal bone advancement. A preliminary study (in press) indicated a significant increase in intracranial and ventricular volume following frontal bone advancement. Pre- and post- operative CT scans, which are acquired as part of the normal routine for care of such patients, provide the necessary data. CT slices of 1.5 mm through the cranial vault will be analyzed by CEMAX-1000 computer system, which will summate the 3D slices from areas of interest and calculate volume. Approximately 30 patients between 6 and 12 months of age will be studied. CT scans will be performed within one week of surgery, and 2 to 4 weeks after surgery.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Program Projects (P01)
Project #
2P01DE003568-12A1
Application #
3940083
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Type
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012

  Publications

Bookstein, F L; Grayson, B; Cutting, C B et al. (1991) Landmarks in three dimensions: reconstruction from cephalograms versus direct observation. Am J Orthod Dentofacial Orthop 100:133-40
McCarthy, J G; La Trenta, G S; Breitbart, A S et al. (1990) The Le Fort III advancement osteotomy in the child under 7 years of age. Plast Reconstr Surg 86:633-46;discussion 647-9
Stuzin, J M; Cutting, C B; McCarthy, J G et al. (1988) Radiographical documentation of direct injury of the intracanalicular segment of the optic nerve in the orbital apex syndrome. Ann Plast Surg 20:368-73
Cutting, C B; McCarthy, J G; Karron, D B (1988) Three-dimensional input of body surface data using a laser light scanner. Ann Plast Surg 21:38-45
Grayson, B; Cutting, C; Bookstein, F L et al. (1988) The three-dimensional cephalogram: theory, technique, and clinical application. Am J Orthod Dentofacial Orthop 94:327-37
LaTrenta, G S; McCarthy, J G; Cutting, C B (1987) The growth of vascularized onlay bone transfers. Ann Plast Surg 18:511-6
Dufresne, C R; McCarthy, J G; Cutting, C B et al. (1987) Volumetric quantification of intracranial and ventricular volume following cranial vault remodeling: a preliminary report. Plast Reconstr Surg 79:24-32
Grayson, B H; Bookstein, F L; McCarthy, J G (1986) The mandible in mandibulofacial dysostosis: a cephalometric study. Am J Orthod 89:393-8
Cutting, C; Bookstein, F L; Grayson, B et al. (1986) Three-dimensional computer-assisted design of craniofacial surgical procedures: optimization and interaction with cephalometric and CT-based models. Plast Reconstr Surg 77:877-87
Pensler, J; McCarthy, J G (1985) The calvarial donor site: an anatomic study in cadavers. Plast Reconstr Surg 75:648-51

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