A program of experimentation involves maxillofacial growth studies in animal subjects. Objectives include elucidation of normal and abnormal growth mechanisms which may operate in human patients having craniofacial developmental anomalies. Emphasis is on identification of physical variables in cleft lip and palate habilitation which may play roles in aberrant modification of post-treatment growth and function. Recent attention has focused on the normal contraction phase of surgical wound healing in palatal mucoperiosteum and on the possible interrelationships with postsurgical maxillofacial growth.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Program Projects (P01)
Project #
3P01DE005837-05S1
Application #
3963872
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Jones, David L; Morris, Hughlett L; Van Demark, Duane R (2004) A comparison of oral-nasal balance patterns in speakers who are categorized as ""almost but not quite"" and ""sometimes but not always"". Cleft Palate Craniofac J 41:526-34
Millard, T; Richman, L C (2001) Different cleft conditions, facial appearance, and speech: relationship to psychological variables. Cleft Palate Craniofac J 38:68-75
Jones, D L (2000) The relationship between temporal aspects of oral-nasal balance and classification of velopharyngeal status in speakers with cleft palate. Cleft Palate Craniofac J 37:363-9
Solursh, M; Langille, R M; Wood, J et al. (1996) Osteogenic protein-1 is required for mammalian eye development. Biochem Biophys Res Commun 218:438-43
Dixit, U B; Kelly, K M; Squier, C A et al. (1995) Periosteum in regeneration of palatal defects. Cleft Palate Craniofac J 32:228-34
Hardin-Jones, M A; Brown, C K; Van Demark, D R et al. (1993) Long-term speech results of cleft palate patients with primary palatoplasty. Cleft Palate Craniofac J 30:55-63
Kuehn, D P; Moon, J B; Folkins, J W (1993) Levator veli palatini muscle activity in relation to intranasal air pressure variation. Cleft Palate Craniofac J 30:361-8
Van Demark, D R; Hardin-Jones, M A; O'Gara, M M et al. (1993) Identification of children with and without cleft palate from tape-recorded samples of early vocalizations and speech. Cleft Palate Craniofac J 30:557-63
Hardin, M A; Van Demark, D R; Morris, H L et al. (1992) Correspondence between nasalance scores and listener judgments of hypernasality and hyponasality. Cleft Palate Craniofac J 29:346-51
Archer, C W; Langille, R M; Teran, M A et al. (1992) Myogenic potential of chick limb bud mesenchyme in micromass culture. Anat Embryol (Berl) 185:299-306

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