This program of research is designed to provide continuing acquisition of information needed for improving care of cleft lip and palate patients. Emphasis is on attainment of knowledge to enable the most effective physical management at the earliest possible age. Primary focus is on cleft lip and palate surgery as it influences developmental anatomy and physiology with regard to maxillofacial esthetics, speech production, and function. Some additional focus is on the child with cleft lip and palate and psychoeducational aspects. An overall long-term objective is to attain increased control of treatment outcome by better understanding the various mechanisms. Both human and animal subjects will be used. Data from previous studies will serve as the basis for efficient and effective utilization of new data to be collected.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Program Projects (P01)
Project #
5P01DE005837-07
Application #
3094953
Study Section
(SSS)
Project Start
1981-06-01
Project End
1991-11-30
Budget Start
1987-12-01
Budget End
1988-11-30
Support Year
7
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Jones, David L; Morris, Hughlett L; Van Demark, Duane R (2004) A comparison of oral-nasal balance patterns in speakers who are categorized as ""almost but not quite"" and ""sometimes but not always"". Cleft Palate Craniofac J 41:526-34
Millard, T; Richman, L C (2001) Different cleft conditions, facial appearance, and speech: relationship to psychological variables. Cleft Palate Craniofac J 38:68-75
Jones, D L (2000) The relationship between temporal aspects of oral-nasal balance and classification of velopharyngeal status in speakers with cleft palate. Cleft Palate Craniofac J 37:363-9
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Dixit, U B; Kelly, K M; Squier, C A et al. (1995) Periosteum in regeneration of palatal defects. Cleft Palate Craniofac J 32:228-34
Hardin-Jones, M A; Brown, C K; Van Demark, D R et al. (1993) Long-term speech results of cleft palate patients with primary palatoplasty. Cleft Palate Craniofac J 30:55-63
Kuehn, D P; Moon, J B; Folkins, J W (1993) Levator veli palatini muscle activity in relation to intranasal air pressure variation. Cleft Palate Craniofac J 30:361-8
Van Demark, D R; Hardin-Jones, M A; O'Gara, M M et al. (1993) Identification of children with and without cleft palate from tape-recorded samples of early vocalizations and speech. Cleft Palate Craniofac J 30:557-63
Hardin, M A; Van Demark, D R; Morris, H L et al. (1992) Correspondence between nasalance scores and listener judgments of hypernasality and hyponasality. Cleft Palate Craniofac J 29:346-51
Archer, C W; Langille, R M; Teran, M A et al. (1992) Myogenic potential of chick limb bud mesenchyme in micromass culture. Anat Embryol (Berl) 185:299-306

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