Abstract

This program of research is designed to provide continuing acquisition of information needed for improving care of cleft lip and palate patients. Emphasis is on attainment of knowledge to enable the most effective physical management at the earliest possible age. Primary focus is on cleft lip and palate surgery as it influences developmental anatomy and physiology with regard to maxillofacial esthetics, speech production, and function. Some additional focus is on the child with cleft lip and palate and psychoeducational aspects. An overall long-term objective is to attain increased control of treatment outcome by better understanding the various mechanisms. Both human and animal subjects will be used. Data from previous studies will serve as the basis for efficient and effective utilization of new data to be collected.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Program Projects (P01)
Project #
5P01DE005837-08
Application #
3094954
Study Section
(SSS)
Project Start
1981-06-01
Project End
1991-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
8
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
University of Iowa
Department
Type
Schools of Medicine
DUNS #
041294109
City
Iowa City
State
IA
Country
United States
Zip Code
52242

  Publications

Jones, David L; Morris, Hughlett L; Van Demark, Duane R (2004) A comparison of oral-nasal balance patterns in speakers who are categorized as ""almost but not quite"" and ""sometimes but not always"". Cleft Palate Craniofac J 41:526-34
Millard, T; Richman, L C (2001) Different cleft conditions, facial appearance, and speech: relationship to psychological variables. Cleft Palate Craniofac J 38:68-75
Jones, D L (2000) The relationship between temporal aspects of oral-nasal balance and classification of velopharyngeal status in speakers with cleft palate. Cleft Palate Craniofac J 37:363-9
Solursh, M; Langille, R M; Wood, J et al. (1996) Osteogenic protein-1 is required for mammalian eye development. Biochem Biophys Res Commun 218:438-43
Dixit, U B; Kelly, K M; Squier, C A et al. (1995) Periosteum in regeneration of palatal defects. Cleft Palate Craniofac J 32:228-34
Hardin-Jones, M A; Brown, C K; Van Demark, D R et al. (1993) Long-term speech results of cleft palate patients with primary palatoplasty. Cleft Palate Craniofac J 30:55-63
Kuehn, D P; Moon, J B; Folkins, J W (1993) Levator veli palatini muscle activity in relation to intranasal air pressure variation. Cleft Palate Craniofac J 30:361-8
Van Demark, D R; Hardin-Jones, M A; O'Gara, M M et al. (1993) Identification of children with and without cleft palate from tape-recorded samples of early vocalizations and speech. Cleft Palate Craniofac J 30:557-63
Archer, C W; Langille, R M; Teran, M A et al. (1992) Myogenic potential of chick limb bud mesenchyme in micromass culture. Anat Embryol (Berl) 185:299-306
Suzuki, H R; Sakamoto, H; Yoshida, T et al. (1992) Localization of HstI transcripts to the apical ectodermal ridge in the mouse embryo. Dev Biol 150:219-22

Showing the most recent 10 out of 51 publications