The Peptide Core provides the Program Project with a highly-responsive, in-house resource for peptide synthesis and chemical-analytical services and expertise through the following activities: 1. Preparation of synthetic peptides and analogs over a range of scales, followed by documentation of their homogeneity; 2. Performance of sequencing, mass spectroscopy, and amino acid compositional analyses of peptides and biosynthetic products; 3. Development and application of specialized chemical procedures such as crosslinking, prosthetic group attachment and """"""""customized"""""""" purification modalities; 4. Micro- and macro-scale purification of proteins and peptides using HPLC and other chromatographic modalities 5. Advice and consultation in synthesis and purification strategies and """"""""hands-on"""""""" transfer of technologies to participating investigators.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK011794-37
Application #
7062736
Study Section
Special Emphasis Panel (ZDK1)
Project Start
2004-12-01
Project End
2008-11-30
Budget Start
2004-12-01
Budget End
2005-11-30
Support Year
37
Fiscal Year
2005
Total Cost
$187,378
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
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