Project Start
1999-04-01
Project End
2000-03-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
14
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Bhatia, Vandanajay; Cao, Yanna; Ko, Tien C et al. (2016) Parathyroid Hormone-Related Protein Interacts With the Transforming Growth Factor-?/Bone Morphogenetic Protein-2/Gremlin Signaling Pathway to Regulate Proinflammatory and Profibrotic Mediators in Pancreatic Acinar and Stellate Cells. Pancreas 45:659-70
Staloch, Dustin; Gao, Xuxia; Liu, Ka et al. (2015) Gremlin is a key pro-fibrogenic factor in chronic pancreatitis. J Mol Med (Berl) 93:1085-1093
Mrazek, Amy A; Porro, Laura J; Bhatia, Vandanajay et al. (2015) Apigenin inhibits pancreatic stellate cell activity in pancreatitis. J Surg Res 196:8-16
Gao, Xuxia; Cao, Yanna; Staloch, Dustin A et al. (2014) Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis. PLoS One 9:e89114
Bhatia, Vandanajay; Rastellini, Cristiana; Han, Song et al. (2014) Acinar cell-specific knockout of the PTHrP gene decreases the proinflammatory and profibrotic responses in pancreatitis. Am J Physiol Gastrointest Liver Physiol 307:G533-49
Gao, Xuxia; Cao, Yanna; Yang, Wenli et al. (2013) BMP2 inhibits TGF-?-induced pancreatic stellate cell activation and extracellular matrix formation. Am J Physiol Gastrointest Liver Physiol 304:G804-13
Deng, Xiyun; Cao, Yanna; Liu, Yan et al. (2013) Overexpression of Evi-1 oncoprotein represses TGF-? signaling in colorectal cancer. Mol Carcinog 52:255-264
Cao, Yanna; Zhang, Weili; Gao, Xuxia et al. (2013) PTHrP is a novel mediator for TGF-?-induced apoptosis. Regul Pept 184:40-6
Cao, Yanna; Yang, Wenli; Tyler, Matthew A et al. (2013) Noggin attenuates cerulein-induced acute pancreatitis and impaired autophagy. Pancreas 42:301-7
Bhatia, Vandanajay; Kim, Sung O K; Aronson, Judith F et al. (2012) Role of parathyroid hormone-related protein in the pro-inflammatory and pro-fibrogenic response associated with acute pancreatitis. Regul Pept 175:49-60

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