Abstract

The Mouse Husbandry and Genotyping core will support the use within this program: 1) performing routine husbandry of transgenic and gene knock-out mice, 2) determining genotypes of transgenic and gene knock- out mice by PCR analysis of tail DNA, 3) facilitating the cryopreservation of transgenic mice, and 4) distributing transgenic and gene knock-out mice to other investigators.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
2P01DK042502-11
Application #
6352883
Study Section
Project Start
2000-08-15
Project End
2001-06-30
Budget Start
Budget End
Support Year
11
Fiscal Year
2000
Total Cost
$198,779
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Zhang, Juliet; Weinrich, Jarret A P; Russ, Jeffrey B et al. (2017) A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. Cell Rep 21:666-678
Krah, Nathan M; De La O, Jean-Paul; Swift, Galvin H et al. (2015) The acinar differentiation determinant PTF1A inhibits initiation of pancreatic ductal adenocarcinoma. Elife 4:
Baeyens, Luc; Lemper, Marie; Leuckx, Gunter et al. (2014) Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice. Nat Biotechnol 32:76-83
Liu, Jing; Willet, Spencer G; Bankaitis, Eric D et al. (2013) Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulation. Genesis 51:436-42
Kopinke, Daniel; Brailsford, Marisa; Pan, Fong Cheng et al. (2012) Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas. Dev Biol 362:57-64
Gu, Yanyun; Lindner, Jill; Kumar, Anil et al. (2011) Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size. Diabetes 60:827-37
Pound, Lynley D; Hang, Yan; Sarkar, Suparna A et al. (2011) The pancreatic islet ?-cell-enriched transcription factor Pdx-1 regulates Slc30a8 gene transcription through an intronic enhancer. Biochem J 433:95-105
Papizan, James B; Singer, Ruth A; Tschen, Shuen-Ing et al. (2011) Nkx2.2 repressor complex regulates islet ?-cell specification and prevents ?-to-?-cell reprogramming. Genes Dev 25:2291-305
Artner, Isabella; Hang, Yan; Mazur, Magdalena et al. (2010) MafA and MafB regulate genes critical to beta-cells in a unique temporal manner. Diabetes 59:2530-9
Masui, Toshihiko; Swift, Galvin H; Deering, Tye et al. (2010) Replacement of Rbpj with Rbpjl in the PTF1 complex controls the final maturation of pancreatic acinar cells. Gastroenterology 139:270-80

Showing the most recent 10 out of 24 publications