This application describes the Administrative Core (A) for support of the Program Project Grant entitled """"""""Strategies for Improved Shock Wave Lithotripsy"""""""". Under the direction and supervision of the Program Director, an Administrative Assistant housed in the Department of Anatomy at Indiana University, School of Medicine will assume day-to-day responsibilities involving liaison with I.U. fiscal, administrative and purchasing offices;maintain accounting records for individual projects;generate and follow purchase requests;oversee program schedules and records;facilitate communication between the six institutions through FAX transmissions and a Newsletter entitled """"""""On Target"""""""";organize the activities for semi-annual and quarterly meetings of project personnel and any other such activity as required to insure smooth operation of the program. Core A will use an External Advisory Committee to assist the Program Director. The External Advisory Committee members will attend each semi-annual meeting to monitor the quality of the experimental studies, to assess the scientific progress of each project, and suggest future directions for the individual projects of the grant. Each External Advisor will be required to prepare a written critique for a particular project(s). All Program Project investigators will assemble for a quarterly meeting as weli to assist each project leader in integrating the highly specialized data that will be generate by the projects with the goal of determining objective criteria for the safe clinical use of shock wave lithotripsy for stone comminution.

Public Health Relevance

This Program Project will bring together the expertise of twenty-four scientists/clinicians from six different sites. The overall experimental design is complex and each project has numerous interactions that will require careful coordination. For these reasons the Administrative Core is essential to the conduct of this Program Project.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
2P01DK043881-15
Application #
7759405
Study Section
Special Emphasis Panel (ZDK1-GRB-R (M2))
Project Start
2009-07-01
Project End
2014-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
15
Fiscal Year
2009
Total Cost
$139,057
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Zwaschka, Theresa A; Ahn, Justin S; Cunitz, Bryan W et al. (2018) Combined Burst Wave Lithotripsy and Ultrasonic Propulsion for Improved Urinary Stone Fragmentation. J Endourol 32:344-349
Connors, Bret A; Schaefer, Ray B; Gallagher, John J et al. (2018) Preliminary Report on Stone Breakage and Lesion Size Produced by a New Extracorporeal Electrohydraulic (Sparker Array) Discharge Device. Urology 116:213-217
Dai, Jessica C; Dunmire, Barbrina; Sternberg, Kevan M et al. (2018) Retrospective comparison of measured stone size and posterior acoustic shadow width in clinical ultrasound images. World J Urol 36:727-732
Janssen, Karmon M; Brand, Timothy C; Bailey, Michael R et al. (2018) Effect of Stone Size and Composition on Ultrasonic Propulsion Ex Vivo. Urology 111:225-229
Simon, Julianna C; Sapozhnikov, Oleg A; Kreider, Wayne et al. (2018) The role of trapped bubbles in kidney stone detection with the color Doppler ultrasound twinkling artifact. Phys Med Biol 63:025011
Matula, Thomas J; Sapozhnikov, Oleg A; Ostrovsky, Lev A et al. (2018) Ultrasound-based cell sorting with microbubbles: A feasibility study. J Acoust Soc Am 144:41
Williams Jr, James C; Borofsky, Michael S; Bledsoe, Sharon B et al. (2018) Papillary Ductal Plugging is a Mechanism for Early Stone Retention in Brushite Stone Disease. J Urol 199:186-192
Sapozhnikov, Oleg; Nikolaeva, Anastasiia; Bailey, Michael (2018) The effect of shear waves in an elastic sphere on the radiation force from a quasi-Gaussian beam. Proc Meet Acoust 32:
Handa, Rajash K; Territo, Paul R; Blomgren, Philip M et al. (2017) Development of a novel magnetic resonance imaging acquisition and analysis workflow for the quantification of shock wave lithotripsy-induced renal hemorrhagic injury. Urolithiasis 45:507-513
Rosnitskiy, Pavel B; Yuldashev, Petr V; Sapozhnikov, Oleg A et al. (2017) Design of HIFU Transducers for Generating Specified Nonlinear Ultrasound Fields. IEEE Trans Ultrason Ferroelectr Freq Control 64:374-390

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