Project Start
2001-09-30
Project End
2003-06-30
Budget Start
Budget End
Support Year
10
Fiscal Year
2001
Total Cost
$268,419
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Aihara, Eitaro; Montrose, Marshall H (2014) Importance of Ca(2+) in gastric epithelial restitution-new views revealed by real-time in vivo measurements. Curr Opin Pharmacol 19:76-83
Singh, Varsha; Yang, Jianbo; Chen, Tiane-e et al. (2014) Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. Clin Gastroenterol Hepatol 12:27-31
Lin, Rong; Murtazina, Rakhilya; Cha, Boyoung et al. (2011) D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process. Gastroenterology 140:560-71
Hartley, Jane Louise; Zachos, Nicholas C; Dawood, Ban et al. (2010) Mutations in TTC37 cause trichohepatoenteric syndrome (phenotypic diarrhea of infancy). Gastroenterology 138:2388-98, 2398.e1-2
Zachos, Nicholas C; Hodson, Caleb; Kovbasnjuk, Olga et al. (2008) Elevated intracellular calcium stimulates NHE3 activity by an IKEPP (NHERF4) dependent mechanism. Cell Physiol Biochem 22:693-704
Li, Xuhang; Donowitz, Mark (2008) Fractionation of subcellular membrane vesicles of epithelial and nonepithelial cells by OptiPrep density gradient ultracentrifugation. Methods Mol Biol 440:97-110
Lee, Aven; Rayfield, Andrew; Hryciw, Deanne H et al. (2007) Na+-H+ exchanger regulatory factor 1 is a PDZ scaffold for the astroglial glutamate transporter GLAST. Glia 55:119-29
Donowitz, Mark; Singh, Siddharth; Salahuddin, Farah F et al. (2007) Proteome of murine jejunal brush border membrane vesicles. J Proteome Res 6:4068-79
Murtazina, Rakhilya; Kovbasnjuk, Olga; Zachos, Nicholas C et al. (2007) Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus J Biol Chem 282:25141-51
Donowitz, Mark; Li, Xuhang (2007) Regulatory binding partners and complexes of NHE3. Physiol Rev 87:825-72

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