Project Start
1997-06-01
Project End
1998-05-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sun, Zheng; Miller, Russell A; Patel, Rajesh T et al. (2012) Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration. Nat Med 18:934-42
Zhao, G; Moore, D J; Lee, K M et al. (2010) An unexpected counter-regulatory role of IL-10 in B-lymphocyte-mediated transplantation tolerance. Am J Transplant 10:796-801
Yang, Jichun; Wang, Chunjiong; Li, Jing et al. (2009) PANDER binds to the liver cell membrane and inhibits insulin signaling in HepG2 cells. FEBS Lett 583:3009-15
Huang, Xiaolun; Moore, Daniel J; Mohiuddin, Mohammad et al. (2008) Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance. Transplantation 85:675-80
Noorchashm, Hooman; Reed, Amy J; Rostami, Susan Y et al. (2006) B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection. J Immunol 177:7715-22
Quinn 3rd, William J; Noorchashm, Negin; Crowley, Jenni E et al. (2006) Cutting edge: impaired transitional B cell production and selection in the nonobese diabetic mouse. J Immunol 176:7159-64
Yang, Jichun; Wong, Ryan K; Park, MieJung et al. (2006) Leucine regulation of glucokinase and ATP synthase sensitizes glucose-induced insulin secretion in pancreatic beta-cells. Diabetes 55:193-201
Burkhardt, Brant R; Greene, Scott R; White, Peter et al. (2006) PANDER-induced cell-death genetic networks in islets reveal central role for caspase-3 and cyclin-dependent kinase inhibitor 1A (p21). Gene 369:134-41
Burkhardt, Brant R; Yang, Michael C; Robert, Claudia E et al. (2005) Tissue-specific and glucose-responsive expression of the pancreatic derived factor (PANDER) promoter. Biochim Biophys Acta 1730:215-25
Yang, Jichun; Robert, Claudia E; Burkhardt, Brant R et al. (2005) Mechanisms of glucose-induced secretion of pancreatic-derived factor (PANDER or FAM3B) in pancreatic beta-cells. Diabetes 54:3217-28

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