Abstract

(Taken directly from the application) The aim of this Core is to produce high quality whole mount in situ hybridization for the four projects of this Program. This is a labor intensive specialized procedure, albeit one of great importance to the work of each of the projects. The Core will provide the expertise for achieving high quality results. By utilizing an automated, high throughput system the Core will be able to handle the large number of anticipated samples without delaying any of the research efforts. This support service will free the key personnel on each project from the need to devote time to the labor-intensive manual whole mount in situ hybridization procedure, allowing them to devote their efforts to moving their projects forward.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK056246-04
Application #
6657072
Study Section
Project Start
2002-08-01
Project End
2003-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
4
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Chen, J W; Galloway, J L (2017) Using the zebrafish to understand tendon development and repair. Methods Cell Biol 138:299-320
He, Xinjun; Bougioukli, Sofia; Ortega, Brandon et al. (2017) Sox9 positive periosteal cells in fracture repair of the adult mammalian long bone. Bone 103:12-19
Finch, Caleb E; McMahon, Andrew P (2016) Stem cells for all ages, yet hostage to aging. Stem Cell Investig 3:11
Hojo, Hironori; Ohba, Shinsuke; He, Xinjun et al. (2016) Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification. Dev Cell 37:238-53
He, Xinjun; Ohba, Shinsuke; Hojo, Hironori et al. (2016) AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development 143:3012-23
Hojo, Hironori; McMahon, Andrew P; Ohba, Shinsuke (2016) An Emerging Regulatory Landscape for Skeletal Development. Trends Genet 32:774-787
Moore, Talia Y; Organ, Chris L; Edwards, Scott V et al. (2015) Multiple phylogenetically distinct events shaped the evolution of limb skeletal morphologies associated with bipedalism in the jerboas. Curr Biol 25:2785-2794
Ohba, Shinsuke; He, Xinjun; Hojo, Hironori et al. (2015) Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Rep 12:229-43
Kozhemyakina, Elena; Zhang, Minjie; Ionescu, Andreia et al. (2015) Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. Arthritis Rheumatol 67:1261-73
Hirai, Takao; Kobayashi, Tatsuya; Nishimori, Shigeki et al. (2015) Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis. Endocrinology 156:2774-80

Showing the most recent 10 out of 79 publications