Abstract

The High Resolution Histology Core will serve all the three projects of this Program Project in processing, embedding, cutting and staining the various histology specimens. Furthermore, the Core will assist the investigators of each project in experimental procedures such as in situ hybridization and immunohistochemistry, if requested. Lastly, the Core will assist the individual investigators with measurements of bone densitometry by Piximus. The management of the Core by Dr. Ernestina Schipani will assure the good coordination of the work, and equitable use of core resources, and the efficient use of the equipment.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK056246-10
Application #
7848829
Study Section
Special Emphasis Panel (ZDK1)
Project Start
Project End
Budget Start
2009-06-01
Budget End
2010-05-31
Support Year
10
Fiscal Year
2009
Total Cost
$90,930
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Chen, J W; Galloway, J L (2017) Using the zebrafish to understand tendon development and repair. Methods Cell Biol 138:299-320
He, Xinjun; Bougioukli, Sofia; Ortega, Brandon et al. (2017) Sox9 positive periosteal cells in fracture repair of the adult mammalian long bone. Bone 103:12-19
Hojo, Hironori; McMahon, Andrew P; Ohba, Shinsuke (2016) An Emerging Regulatory Landscape for Skeletal Development. Trends Genet 32:774-787
Finch, Caleb E; McMahon, Andrew P (2016) Stem cells for all ages, yet hostage to aging. Stem Cell Investig 3:11
Hojo, Hironori; Ohba, Shinsuke; He, Xinjun et al. (2016) Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification. Dev Cell 37:238-53
He, Xinjun; Ohba, Shinsuke; Hojo, Hironori et al. (2016) AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development 143:3012-23
Moore, Talia Y; Organ, Chris L; Edwards, Scott V et al. (2015) Multiple phylogenetically distinct events shaped the evolution of limb skeletal morphologies associated with bipedalism in the jerboas. Curr Biol 25:2785-2794
Ohba, Shinsuke; He, Xinjun; Hojo, Hironori et al. (2015) Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte. Cell Rep 12:229-43
Kozhemyakina, Elena; Zhang, Minjie; Ionescu, Andreia et al. (2015) Identification of a Prg4-expressing articular cartilage progenitor cell population in mice. Arthritis Rheumatol 67:1261-73
Hirai, Takao; Kobayashi, Tatsuya; Nishimori, Shigeki et al. (2015) Bone Is a Major Target of PTH/PTHrP Receptor Signaling in Regulation of Fetal Blood Calcium Homeostasis. Endocrinology 156:2774-80

Showing the most recent 10 out of 79 publications