The Administrafive Core serves all four Projects and the Animal Model Core of the Program Project providing coordinafion, communication services, financial and budgetary services, and other financial and administrative services to the individual Project directors. Coordination between the P.l. and the project directors is maintained and facilitated by administrative personnel. Core personnel arrange regular meefings of invesfigators and distribute pertinent scientific information, progress reports, and internal and external project reviews. Financial services include monitoring the budgets of the individual projects, providing invesfigators with financial information, approving expenditures and providing purchasing assistance, and consolidafion and complefion of progress reports. The Administrative Core also serves as the liaison for the scheduling of yeariy Advisory Committee meetings.

Public Health Relevance

Inflammatory Bowel Disease afflicts 1.4 million Americans. The Projects in this Program will increase our understanding of theimmune and genefic mechanisms involved in IBD. This Core will provide necessary administrative support and coordinafion forthe Program.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
2P01DK071176-06
Application #
7992807
Study Section
Special Emphasis Panel (ZDK1-GRB-7 (M1))
Project Start
2010-08-01
Project End
2015-07-31
Budget Start
2010-08-01
Budget End
2011-07-31
Support Year
6
Fiscal Year
2010
Total Cost
$78,431
Indirect Cost
Name
University of Alabama Birmingham
Department
Type
DUNS #
063690705
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Cao, Wei; Kayama, Hisako; Chen, Mei Lan et al. (2017) The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids. Immunity 47:1182-1196.e10
Zhao, Qing; Harbour, Stacey N; Kolde, Raivo et al. (2017) Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota. J Immunol 199:312-322
Tanner, Scott M; Daft, Joseph G; Hill, Stephanie A et al. (2016) Altered T-Cell Balance in Lymphoid Organs of a Mouse Model of Colorectal Cancer. J Histochem Cytochem 64:753-767
Pike, Brian L; Paden, Katie Ann; Alcala, Ashley N et al. (2015) Immunological Biomarkers in Postinfectious Irritable Bowel Syndrome. J Travel Med 22:242-50
Christmann, Benjamin S; Abrahamsson, Thomas R; Bernstein, Charles N et al. (2015) Human seroreactivity to gut microbiota antigens. J Allergy Clin Immunol 136:1378-86.e1-5
Singer, Jeffrey R; Weaver, Casey T (2015) Daughter's Tolerance of Mom Matters in Mate Choice. Cell 162:467-9
Tanner, Scott M; Berryhill, Taylor F; Ellenburg, James L et al. (2015) Pathogenesis of necrotizing enterocolitis: modeling the innate immune response. Am J Pathol 185:4-16
Daft, Joseph G; Lorenz, Robin G (2015) Role of the gastrointestinal ecosystem in the development of type 1 diabetes. Pediatr Diabetes 16:407-18
Harbour, Stacey N; Maynard, Craig L; Zindl, Carlene L et al. (2015) Th17 cells give rise to Th1 cells that are required for the pathogenesis of colitis. Proc Natl Acad Sci U S A 112:7061-6
Hepworth, Matthew R; Fung, Thomas C; Masur, Samuel H et al. (2015) Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4? T cells. Science 348:1031-5

Showing the most recent 10 out of 76 publications