Abstract

The administrative core is composed of three components;the director, the administrator and the advisory committee. Each component is critical to the functioning of the PPG at a different level but like the PPG itself, it is highly interactive.
The aims of this core are: 1. to provide a platform to foster interactive science 2. to incorporate input from our external advisory committee 3. provide resources to help in budgeting and grants management 4. to organize yearly conferences on topics relevant to the grant

Public Health Relevance

The administrative core provides a forum for all investigators to share their work and get immediate feedback. It also creates the interactive environment to allow for advancement of the program as a whole.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Program Projects (P01)
Project #
5P01DK072201-09
Application #
8730613
Study Section
Special Emphasis Panel (ZDK1-GRB-8)
Project Start
Project End
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
9
Fiscal Year
2014
Total Cost
$72,670
Indirect Cost
$29,797

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Meisel, Marlies; Hinterleitner, Reinhard; Pacis, Alain et al. (2018) Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host. Nature 557:580-584
Blander, J Magarian (2018) Regulation of the Cell Biology of Antigen Cross-Presentation. Annu Rev Immunol 36:717-753
Blander, J Magarian; Barbet, Gaetan (2018) Exploiting vita-PAMPs in vaccines. Curr Opin Pharmacol 41:128-136
Barbet, Gaetan; Sander, Leif E; Geswell, Matthew et al. (2018) Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses. Immunity 48:584-598.e5
Moretti, Julien; Blander, J Magarian (2017) Cell-autonomous stress responses in innate immunity. J Leukoc Biol 101:77-86
Blander, J Magarian; Longman, Randy S; Iliev, Iliyan D et al. (2017) Regulation of inflammation by microbiota interactions with the host. Nat Immunol 18:851-860
Blander, J Magarian (2017) The many ways tissue phagocytes respond to dying cells. Immunol Rev 277:158-173
Tang, Mei San; Bowcutt, Rowann; Leung, Jacqueline M et al. (2017) Integrated Analysis of Biopsies from Inflammatory Bowel Disease Patients Identifies SAA1 as a Link Between Mucosal Microbes with TH17 and TH22 Cells. Inflamm Bowel Dis 23:1544-1554
Moretti, Julien; Roy, Soumit; Bozec, Dominique et al. (2017) STING Senses Microbial Viability to Orchestrate Stress-Mediated Autophagy of the Endoplasmic Reticulum. Cell 171:809-823.e13
Campisi, Laura; Barbet, Gaetan; Ding, Yi et al. (2016) Apoptosis in response to microbial infection induces autoreactive TH17 cells. Nat Immunol 17:1084-92

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