The primary, service-oriented goal of the Exposure Assessment Core is to provide a high-quality, comprehensive and cost-effective resource in exposure assessment for all of the research projects within the Center. The secondary, research-oriented goal is to develop and evaluate new approaches to the assessment and quantification of children's exposures to EDs and other developmental toxicants in the urban environment. Objectives of the core, which remain unchanged since the previous application, are to do the following: ascertain new developmental toxicants in the urban environment; identify and develop markers of exposure that will permit precise individual assessment of environmental exposures in infants and children; quantify children's exposures to known environmental toxicants, using analyses of environmental as well as of biological samples; evaluate and quantify exposure pathways; access and store environmental and biological samples; and provide quality assurance/quality control (QA/QC) for all analyses conducted in Center projects.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES009584-10
Application #
7523235
Study Section
Special Emphasis Panel (ZES1)
Project Start
Project End
Budget Start
2007-11-01
Budget End
2008-10-31
Support Year
10
Fiscal Year
2008
Total Cost
$106,268
Indirect Cost
Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029
Dobraca, Dina; Lum, Raymond; Sjödin, Andreas et al. (2018) Urinary biomarkers of polycyclic aromatic hydrocarbons in pre- and peri-pubertal girls in Northern California: Predictors of exposure and temporal variability. Environ Res 165:46-54
Buckley, Jessie P; Quirós-Alcalá, Lesliam; Teitelbaum, Susan L et al. (2018) Associations of prenatal environmental phenol and phthalate biomarkers with respiratory and allergic diseases among children aged 6 and 7?years. Environ Int 115:79-88
Furlong, Melissa; Herring, Amy H; Goldman, Barbara D et al. (2018) Early Life Characteristics and Neurodevelopmental Phenotypes in the Mount Sinai Children's Environmental Health Center. Child Psychiatry Hum Dev 49:534-550
Keil, Alexander P; Daza, Eric J; Engel, Stephanie M et al. (2018) A Bayesian approach to the g-formula. Stat Methods Med Res 27:3183-3204
Furlong, Melissa A; Barr, Dana Boyd; Wolff, Mary S et al. (2017) Prenatal exposure to pyrethroid pesticides and childhood behavior and executive functioning. Neurotoxicology 62:231-238
Singer, Alison B; Wolff, Mary S; Silva, Manori J et al. (2017) Prenatal phthalate exposures and child temperament at 12 and 24 months. Neurotoxicology 62:248-257
Wolff, Mary S; Pajak, Ashley; Pinney, Susan M et al. (2017) Associations of urinary phthalate and phenol biomarkers with menarche in a multiethnic cohort of young girls. Reprod Toxicol 67:56-64
Hiatt, Robert A; Stewart, Susan L; Hoeft, Kristin S et al. (2017) Childhood Socioeconomic Position and Pubertal Onset in a Cohort of Multiethnic Girls: Implications for Breast Cancer. Cancer Epidemiol Biomarkers Prev 26:1714-1721
Windham, Gayle C; Lum, Raymond; Voss, Robert et al. (2017) Age at Pubertal Onset in Girls and Tobacco Smoke Exposure During Pre- and Postnatal Susceptibility Windows. Epidemiology 28:719-727
Buckley, Jessie P; Doherty, Brett T; Keil, Alexander P et al. (2017) Statistical Approaches for Estimating Sex-Specific Effects in Endocrine Disruptors Research. Environ Health Perspect 125:067013

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