Abstract

Public Health Relevance

These studies will ascertain how environmental exposures may be responsible for the neurodevelopmental and neurobehavieral disorders that are seen in the U.S. overall and in our target population. An understanding of how epigenetic mechanisms may be responsible for mediating the effects of prenatal exposures on these adverse health outcomes will allow targeted interventions to prevent long-term effects on children's health

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
2P01ES009600-11
Application #
7854864
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Project Start
Project End
Budget Start
2009-09-24
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$199,530
Indirect Cost

  Institution

Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032

  Publications

Wheelock, Kylie; Zhang, Junfeng Jim; McConnell, Rob et al. (2018) A novel method for source-specific hemoglobin adducts of nitro-polycyclic aromatic hydrocarbons. Environ Sci Process Impacts :
Bansal, Ravi; Peterson, Bradley S (2018) Cluster-level statistical inference in fMRI datasets: The unexpected behavior of random fields in high dimensions. Magn Reson Imaging 49:101-115
Lovinsky-Desir, Stephanie; Lawrence, Jennifer; Jung, Kyung Hwa et al. (2018) Assessment of exposure to air pollution in children: Determining whether wearing a personal monitor affects physical activity. Environ Res 166:340-343
Perera, Frederica P; Wheelock, Kylie; Wang, Ya et al. (2018) Combined effects of prenatal exposure to polycyclic aromatic hydrocarbons and material hardship on child ADHD behavior problems. Environ Res 160:506-513
Jung, Kyung Hwa; Lovinsky-Desir, Stephanie; Yan, Beizhan et al. (2017) Effect of personal exposure to black carbon on changes in allergic asthma gene methylation measured 5 days later in urban children: importance of allergic sensitization. Clin Epigenetics 9:61
Lovinsky-Desir, Stephanie; Jung, Kyung Hwa; Jezioro, Jacqueline R et al. (2017) Physical activity, black carbon exposure, and DNA methylation in the FOXP3 promoter. Clin Epigenetics 9:65
Jung, Kyung Hwa; Torrone, David; Lovinsky-Desir, Stephanie et al. (2017) Short-term exposure to PM2.5 and vanadium and changes in asthma gene DNA methylation and lung function decrements among urban children. Respir Res 18:63
Perera, Frederica; Nolte, Emily L Roen; Wang, Ya et al. (2016) Bisphenol A exposure and symptoms of anxiety and depression among inner city children at 10-12 years of age. Environ Res 151:195-202
Miller, Rachel L; Yan, Zhonghai; Maher, Christina et al. (2016) Impact of prenatal polycyclic aromatic hydrocarbon exposure on behavior, cortical gene expression and DNA methylation of the Bdnf gene. Neuroepigenetics 5:11-18
Engel, Stephanie M; Bradman, Asa; Wolff, Mary S et al. (2016) Prenatal Organophosphorus Pesticide Exposure and Child Neurodevelopment at 24 Months: An Analysis of Four Birth Cohorts. Environ Health Perspect 124:822-30

Showing the most recent 10 out of 153 publications