Public Health Relevance

Children may be susceptible to adverse effects of environmental exposures depending on their genetic make-up and expression of key enzymes. Epigenetic markers, including DNA methylation, play an important role in disease and development. The associations between methylation in children and eariy life exposures, sex, age,and onset of puberty are unknown. This information from minority children is imperative for completing the Human Epigenome Project and informing policy decisions to protect children's health.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
2P01ES009605-11
Application #
7852996
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Project Start
Project End
Budget Start
2009-09-24
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$149,937
Indirect Cost
Name
University of California Berkeley
Department
Type
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
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Huen, Karen; Solomon, Olivia; Kogut, Katherine et al. (2018) PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure. Environ Int 121:31-40
Sagiv, Sharon K; Harris, Maria H; Gunier, Robert B et al. (2018) Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture. Environ Health Perspect 126:047012
Torres, Jacqueline M; Deardorff, Julianna; Gunier, Robert B et al. (2018) Worry About Deportation and Cardiovascular Disease Risk Factors Among Adult Women: The Center for the Health Assessment of Mothers and Children of Salinas Study. Ann Behav Med 52:186-193

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