This Children's Centerfor Environmental Health Research Program Project will examine a set of endocrine disrupting and neurotoxic chemicals to which children living in agricultural communities in California may be particularly exposed: DDT, Mn, and PBDEs. We will examine the pathways and levels of exposures to children, the effects ofthese exposures on their neurodevelopment and pubertal development, and possible epigenetic mechanisms of action of these compounds. The overall goal is to reduce children's exposures and the Administrative Core will coordinate these efforts.
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