Public Health Relevance

This Children's Centerfor Environmental Health Research Program Project will examine a set of endocrine disrupting and neurotoxic chemicals to which children living in agricultural communities in California may be particularly exposed: DDT, Mn, and PBDEs. We will examine the pathways and levels of exposures to children, the effects ofthese exposures on their neurodevelopment and pubertal development, and possible epigenetic mechanisms of action of these compounds. The overall goal is to reduce children's exposures and the Administrative Core will coordinate these efforts.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
2P01ES009605-11
Application #
7853020
Study Section
Special Emphasis Panel (ZES1-LKB-G (P1))
Project Start
Project End
Budget Start
2009-09-24
Budget End
2010-07-31
Support Year
11
Fiscal Year
2009
Total Cost
$70,051
Indirect Cost
Name
University of California Berkeley
Department
Type
DUNS #
124726725
City
Berkeley
State
CA
Country
United States
Zip Code
94704
Mora, Ana M; Fleisch, Abby F; Rifas-Shiman, Sheryl L et al. (2018) Early life exposure to per- and polyfluoroalkyl substances and mid-childhood lipid and alanine aminotransferase levels. Environ Int 111:1-13
Gunier, Robert B; Raanan, Rachel; Castorina, Rosemary et al. (2018) Residential proximity to agricultural fumigant use and respiratory health in 7-year old children. Environ Res 164:93-99
Tindula, Gwen; Murphy, Susan K; Grenier, Carole et al. (2018) DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure. Epigenomics 10:1011-1026
Gonzales, Nancy A; Johnson, Megan; Shirtcliff, Elizabeth A et al. (2018) The role of bicultural adaptation, familism, and family conflict in Mexican American adolescents' cortisol reactivity. Dev Psychopathol 30:1571-1587
Felix, Janine F; Joubert, Bonnie R; Baccarelli, Andrea A et al. (2018) Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol 47:22-23u
Berger, Kimberly; Eskenazi, Brenda; Balmes, John et al. (2018) Associations between prenatal maternal urinary concentrations of personal care product chemical biomarkers and childhood respiratory and allergic outcomes in the CHAMACOS study. Environ Int 121:538-549
Sjödin, Andreas; Jones, Richard S; Gunier, Robert B et al. (2018) Polybrominated Diphenyl Ethers, Polychlorinated Biphenyls, and 2,2-Bis(4-chlorophenyl)-1,1-dichloroethene in 7- and 9-Year-Old Children and Their Mothers in the Center for the Health Assessment of Mothers and Children of Salinas Cohort. Environ Sci Technol 52:2287-2294
Huen, Karen; Solomon, Olivia; Kogut, Katherine et al. (2018) PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure. Environ Int 121:31-40
Sagiv, Sharon K; Harris, Maria H; Gunier, Robert B et al. (2018) Prenatal Organophosphate Pesticide Exposure and Traits Related to Autism Spectrum Disorders in a Population Living in Proximity to Agriculture. Environ Health Perspect 126:047012
Torres, Jacqueline M; Deardorff, Julianna; Gunier, Robert B et al. (2018) Worry About Deportation and Cardiovascular Disease Risk Factors Among Adult Women: The Center for the Health Assessment of Mothers and Children of Salinas Study. Ann Behav Med 52:186-193

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