The Administrative Core will assist the center Director, M-F. Chesselet and Center Co-Director, B. Ritz in the management of the Center and provide support for the Center's educational and collaborative activities. The Core will organize weekly meetings of Center Project leaders and co-investigators and monthly meetings of the Steering Committee of the Center. It will coordinate with other PD research groups, in particular the UCLA Udall Center, and organizea monthly meeting of-Center researchers and an annual symposium on PD research opened to the UCLA community. These activities will provide an opportunity to rigorously follow progress of Center projects and to cross-train investigators from different backgrounds and disciplines involved in Center research. The Core will be responsible for the organization of the annual visit of the External Advisory Board of the Center to UCLA and will provide support for collaborative projects of the Center by organizing visits of investigators from other CNs to UCLA and the participation of Center investigators to NIEHS-sponsored investigator meetings. Finally, the Core will provide support for preparation of reports, dissemination of information about PD research within the Center, and dissemination of data and protocols from the Center through postings on the Center website.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES016732-04
Application #
8292139
Study Section
Special Emphasis Panel (ZES1)
Project Start
2011-07-01
Project End
2013-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
4
Fiscal Year
2011
Total Cost
$163,446
Indirect Cost
Name
University of California Los Angeles
Department
Type
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
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Paul, Kimberly C; Sinsheimer, Janet S; Cockburn, Myles et al. (2018) NFE2L2, PPARGC1?, and pesticides and Parkinson's disease risk and progression. Mech Ageing Dev 173:1-8
Chen, Honglei; Ritz, Beate (2018) The Search for Environmental Causes of Parkinson's Disease: Moving Forward. J Parkinsons Dis 8:S9-S17
Richter, Franziska; Subramaniam, Sudhakar R; Magen, Iddo et al. (2017) A Molecular Tweezer Ameliorates Motor Deficits in Mice Overexpressing ?-Synuclein. Neurotherapeutics 14:1107-1119
Sanders, Laurie H; Paul, Kimberly C; Howlett, Evan H et al. (2017) Editor's Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson's Disease Risk. Toxicol Sci 158:188-198
Aguilar, Jenny I; Dunn, Matthew; Mingote, Susana et al. (2017) Neuronal Depolarization Drives Increased Dopamine Synaptic Vesicle Loading via VGLUT. Neuron 95:1074-1088.e7
Paul, Kimberly C; Sinsheimer, Janet S; Cockburn, Myles et al. (2017) Organophosphate pesticides and PON1 L55M in Parkinson's disease progression. Environ Int 107:75-81
Chuang, Yu-Hsuan; Paul, Kimberly C; Bronstein, Jeff M et al. (2017) Parkinson's disease is associated with DNA methylation levels in human blood and saliva. Genome Med 9:76
Richter, Franziska; Gabby, Lauryn; McDowell, Kimberly A et al. (2017) Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiol Aging 51:54-66
Narayan, Shilpa; Liew, Zeyan; Bronstein, Jeff M et al. (2017) Occupational pesticide use and Parkinson's disease in the Parkinson Environment Gene (PEG) study. Environ Int 107:266-273

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