Abstract

Although mouse allergen and pollutant exposures have been linked to asthma morbidity in poor minority populations, these factors do not account for most of the observed morbidity, so that additional environmental factors almost certainly contribute to asthma morbidity in this population. One intriguing environmental factor is diet since the population that is most affected by asthma morbidity and mortality-poor, predominantly African American populations- have a

Public Health Relevance

Findings from the proposed studies will lend insight into impact of dietary factors on inner-city asthma. Specifically, the project will determine if dietary interventions can improve oxidative stress status, inflammation, and allergic asthma. The findings may support the use of dietary supplement or overhaul of diet in the treatment of allergic asthma.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
5P01ES018176-05
Application #
8528591
Study Section
Special Emphasis Panel (ZES1-LKB-G)
Project Start
Project End
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
5
Fiscal Year
2013
Total Cost
$150,848
Indirect Cost
$46,070

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Wu, Tianshi David; Eakin, Michelle N; Rand, Cynthia S et al. (2018) In-Home Secondhand Smoke Exposure Among Urban Children With Asthma: Contrasting Households With and Without Residential Smokers. J Public Health Manag Pract :
Rice, Jessica L; Brigham, Emily; Dineen, Rebecca et al. (2018) The feasibility of an air purifier and secondhand smoke education intervention in homes of inner city pregnant women and infants living with a smoker. Environ Res 160:524-530
Wu, Tianshi David; Brigham, Emily P; Peng, Roger et al. (2018) Overweight/obesity enhances associations between secondhand smoke exposure and asthma morbidity in children. J Allergy Clin Immunol Pract 6:2157-2159.e5
Peters, Kamau O; Williams, D' Ann L; Abubaker, Salahadin et al. (2017) Predictors of polycyclic aromatic hydrocarbon exposure and internal dose in inner city Baltimore children. J Expo Sci Environ Epidemiol 27:290-298
Nnodum, Benedicta Nneoma; McCormack, Meredith C; Putcha, Nirupama et al. (2017) Impact of Physical Activity on Reporting of Childhood Asthma Symptoms. Lung 195:693-698
Paulin, Laura M; Williams, D 'Ann L; Peng, Roger et al. (2017) 24-h Nitrogen dioxide concentration is associated with cooking behaviors and an increase in rescue medication use in children with asthma. Environ Res 159:118-123
Grant, Torie; Aloe, Charles; Perzanowski, Matthew et al. (2017) Mouse Sensitization and Exposure Are Associated with Asthma Severity in Urban Children. J Allergy Clin Immunol Pract 5:1008-1014.e1
McCormack, Meredith C; Paulin, Laura M; Gummerson, Christine E et al. (2017) Colder temperature is associated with increased COPD morbidity. Eur Respir J 49:
Kolahdooz, Fariba; Butler, Jennie L; Christiansen, Karina et al. (2016) Food and Nutrient Intake in African American Children and Adolescents Aged 5 to 16 Years in Baltimore City. J Am Coll Nutr 35:205-16
McCormack, Meredith C; Belli, Andrew J; Waugh, Darryn et al. (2016) Respiratory Effects of Indoor Heat and the Interaction with Air Pollution in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc 13:2125-2131

Showing the most recent 10 out of 65 publications