The overarching goal of the Community Outreach and Translation Core of the Children's Environmental Health and Disease Prevention Center at Dartmouth is to effectively translate and communicate the research findings from our Center's investigators to the key stakeholders concerned with protection and promotion of children's health. Our Center's focus on in utero and early childhood environmental exposures to arsenic (and other heavy metals) in water and food, and the application of novel biomarkers and research methods to identify mechanisms of the developmental origins of disease pose great scientific promise but also significant risk communication challenges. During the formative phase of our Center's development, much of our work focused on exploration of these issues and communication challenges, in particular those raised by our investigator's studies related to arsenic content in foods. Working closely with our Center's Child Health Specialist we focused our initial community outreach and translation on three groups of key stakeholders: 1) women of childbearing age using private well water sources enrolled in the New Hampshire Birth Cohort Study (the parent study for our Center's research);2) The Dartmouth/Northern New England Primary Care Research Cooperative (COOP), a voluntary, cooperative network of independent clinicians practicing in New Hampshire and other rural communities in Northern New England;and 3) the Mascoma Valley Health Initiative (MVHl), a nonprofit, grassroots, regional public/community health coordinating agency. During this next phase of our Center's development, we will continue to work with and engage these three groups of key stakeholders to collaboratively develop, implement and evaluate ways to improve risk communication and provide technical support regarding the focus of the research of our Center, in utero and early life exposure to arsenic (and other heavy metals) through water and food. Our goals are to integrate environmental health screening into the clinical environment and to create effective materials and methods for risk communication that will advance and inform the research in this area and serve as adaptable models for others working in the fields of children's environmental health and disease prevention.

Public Health Relevance

The COTC will enhance the knowledge of the public, health care providers and study participants of the Center about the risks of environmental exposure to metals, and the regional importance of groundwater arsenic. It will provide valuable tools and resources for clinicians and public health/community practitioners in rural communities to promote well water testing and reduction of exposure to metals in food and water and serve as a model for other programs.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Program Projects (P01)
Project #
3P01ES022832-02S1
Application #
8890329
Study Section
Special Emphasis Panel (ZES1-LKB-K)
Project Start
2014-07-21
Project End
2018-05-31
Budget Start
2014-07-21
Budget End
2015-05-31
Support Year
2
Fiscal Year
2014
Total Cost
$20,004
Indirect Cost
Name
Dartmouth College
Department
Type
DUNS #
041027822
City
Hanover
State
NH
Country
United States
Zip Code
03755
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Emond, Jennifer A; Karagas, Margaret R; Baker, Emily R et al. (2018) Better Diet Quality during Pregnancy Is Associated with a Reduced Likelihood of an Infant Born Small for Gestational Age: An Analysis of the Prospective New Hampshire Birth Cohort Study. J Nutr 148:22-30
Caito, Samuel W; Jackson, Brian P; Punshon, Tracy et al. (2018) Editor's Highlight: Variation in Methylmercury Metabolism and Elimination Status in Humans Following Fish Consumption. Toxicol Sci 161:443-453
Braun, Joseph M; Chen, Aimin; Hoofnagle, Andrew et al. (2018) Associations of early life urinary triclosan concentrations with maternal, neonatal, and child thyroid hormone levels. Horm Behav 101:77-84
Punshon, Tracy; Jackson, Brian P (2018) Essential micronutrient and toxic trace element concentrations in gluten containing and gluten-free foods. Food Chem 252:258-264
White, Alexandra J; O'Brien, Katie M; Jackson, Brian P et al. (2018) Urine and toenail cadmium levels in pregnant women: A reliability study. Environ Int 118:86-91
Felix, Janine F; Joubert, Bonnie R; Baccarelli, Andrea A et al. (2018) Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. Int J Epidemiol 47:22-23u
Everson, Todd M; Marsit, Carmen J (2018) Integrating -Omics Approaches into Human Population-Based Studies of Prenatal and Early-Life Exposures. Curr Environ Health Rep 5:328-337
Chernikova, Diana A; Madan, Juliette C; Housman, Molly L et al. (2018) The premature infant gut microbiome during the first 6 weeks of life differs based on gestational maturity at birth. Pediatr Res 84:71-79
Lester, Barry M; Marsit, Carmen J (2018) Epigenetic mechanisms in the placenta related to infant neurodevelopment. Epigenomics 10:321-333

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