Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM048130-07
Application #
6204246
Study Section
Project Start
1999-08-01
Project End
2000-07-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
7
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Fry, Bryan A; Solomon, Lee A; Leslie Dutton, P et al. (2016) Design and engineering of a man-made diffusive electron-transport protein. Biochim Biophys Acta 1857:513-521
Goparaju, Geetha; Fry, Bryan A; Chobot, Sarah E et al. (2016) First principles design of a core bioenergetic transmembrane electron-transfer protein. Biochim Biophys Acta 1857:503-512
Zelent, Bogumil; Sharp, Kim A; Vanderkooi, Jane M (2010) Differential scanning calorimetry and fluorescence study of lactoperoxidase as a function of guanidinium-HCl, urea, and pH. Biochim Biophys Acta 1804:1508-15
Coleman, Ryan G; Sharp, Kim A (2010) Shape and evolution of thermostable protein structure. Proteins 78:420-33
Coleman, Ryan G; Sharp, Kim A (2010) Protein pockets: inventory, shape, and comparison. J Chem Inf Model 50:589-603
Sharp, Kim A; Vanderkooi, Jane M (2010) Water in the half shell: structure of water, focusing on angular structure and solvation. Acc Chem Res 43:231-9
Zelent, B; Vanderkooi, J M (2009) Infrared spectroscopy used to study ice formation: the effect of trehalose, maltose, and glucose on melting. Anal Biochem 390:215-7
Coleman, Ryan G; Sharp, Kim A (2009) Finding and characterizing tunnels in macromolecules with application to ion channels and pores. Biophys J 96:632-45
Zelent, Bogumil; Vanderkooi, Jane M; Nucci, Nathaniel V et al. (2009) Phosphate assisted proton transfer in water and sugar glasses: a study using fluorescence of pyrene-1-carboxylate and IR spectroscopy. J Fluoresc 19:21-31
Frederick, Kendra King; Sharp, Kim A; Warischalk, Nicholas et al. (2008) Re-evaluation of the model-free analysis of fast internal motion in proteins using NMR relaxation. J Phys Chem B 112:12095-103

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