Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM051630-02
Application #
5212264
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Swartz, Harold M; Taie, Satoshi; Miyake, Minoru et al. (2003) The effects of anesthesia on cerebral tissue oxygen tension: use of EPR oximetry to make repeated measurements. Adv Exp Med Biol 530:569-75
James, Philip E; Madhani, Melanie; Ross, Chris et al. (2003) Tissue hypoxia during bacterial sepsis is attenuated by PR-39, an antibacterial peptide. Adv Exp Med Biol 530:645-52
Hou, Huagang; Grinberg, Oleg Y; Taie, Satoshi et al. (2003) Electron paramagnetic resonance assessment of brain tissue oxygen tension in anesthetized rats. Anesth Analg 96:1467-72, table of contents
Dunn, Jeff F; Swartz, Harold M (2003) In vivo electron paramagnetic resonance oximetry with particulate materials. Methods 30:159-66
Swartz, Harold M; Dunn, Jeff F (2003) Measurements of oxygen in tissues: overview and perspectives on methods. Adv Exp Med Biol 530:1-12
Miyake, Minoru; Grinberg, Oleg Y; Hou, Huagang et al. (2003) The effect of RSR13, a synthetic allosteric modifier of hemoglobin, on brain tissue pO2 (measured by EPR oximetry) following severe hemorrhagic shock in rats. Adv Exp Med Biol 530:319-29
Grinberg, Oleg Y; Miyake, Minoru; Hou, Huagang et al. (2003) The dose-dependent effect of RSR13, a synthetic allosteric modifier of hemoglobin, on physiological parameters and brain tissue oxygenation in rats. Adv Exp Med Biol 530:287-96
Swartz, Harold M (2002) Measuring real levels of oxygen in vivo: opportunities and challenges. Biochem Soc Trans 30:248-52
James, Philip E; Madhani, Melanie; Roebuck, William et al. (2002) Endotoxin-induced liver hypoxia: defective oxygen delivery versus oxygen consumption. Nitric Oxide 6:18-28
James, Philip E; Swartz, Harold M (2002) Simultaneous detection of pO2 and NO by electron paramagnetic resonance. Methods Enzymol 359:52-66

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