Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
1P01GM054160-03
Application #
6271882
Study Section
Project Start
1998-05-01
Project End
1999-06-30
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Yale University
Department
Type
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Alexandrov, Vadim; Lehnert, Ursula; Echols, Nathaniel et al. (2005) Normal modes for predicting protein motions: a comprehensive database assessment and associated Web tool. Protein Sci 14:633-43
Freeman-Cook, Lisa L; Edwards, Anne P B; Dixon, Ann M et al. (2005) Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. J Mol Biol 345:907-21
Balasubramanian, Suganthi; Xia, Yu; Freinkman, Elizaveta et al. (2005) Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms. Nucleic Acids Res 33:1710-21
Lehnert, Ursula; Xia, Yu; Royce, Thomas E et al. (2004) Computational analysis of membrane proteins: genomic occurrence, structure prediction and helix interactions. Q Rev Biophys 37:121-46
Freeman-Cook, Lisa L; Dixon, Ann M; Frank, Jennifer B et al. (2004) Selection and characterization of small random transmembrane proteins that bind and activate the platelet-derived growth factor beta receptor. J Mol Biol 338:907-20
Zhang, Zhaolei; Gerstein, Mark (2003) The human genome has 49 cytochrome c pseudogenes, including a relic of a primordial gene that still functions in mouse. Gene 312:61-72
Schneider, Dirk; Engelman, Donald M (2003) GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane. J Biol Chem 278:3105-11
Lin, J; Qian, J; Greenbaum, D et al. (2002) GeneCensus: genome comparisons in terms of metabolic pathway activity and protein family sharing. Nucleic Acids Res 30:4574-82
Jansen, R; Gerstein, M (2000) Analysis of the yeast transcriptome with structural and functional categories: characterizing highly expressed proteins. Nucleic Acids Res 28:1481-8
MacKenzie, K R; Prestegard, J H; Engelman, D M (1997) A transmembrane helix dimer: structure and implications. Science 276:131-3