The CORE facility is designed to provide support in several technical areas used by all or most of the participants in the program. It offers capabilities in NMR spectroscopy with facilitated access to 500, 600, and 800 MHz instruments, analytical ultracentrifugation using the Beckman XL-I ultracentrifuge, Fourier transform infrared spectroscopy, peptide synthesis, and computational capabilities that include three dimensional structural displays, modeling using molecular dynamics simulation, and database searching. In the period since the initiation of the grant a little more than two years ago, each of these facilities has been created and brought to operational status. While some desirable upgrades are requested, it is felt that the CORE has basically evolved to an excellent state, fully capable of supporting the research proposed for the next grant period if it is appropriately staffed.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
5P01GM054160-06
Application #
6467405
Study Section
Project Start
2001-07-01
Project End
2002-06-30
Budget Start
Budget End
Support Year
6
Fiscal Year
2001
Total Cost
Indirect Cost
Name
Yale University
Department
Type
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
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