Abstract

The Administrative Core will perform all of the business functions requires to ensure the successful administrative oversight of the program. The centralization of supply and equipment purchasing, payroll processing, accounting and grant budget management is designed to provide administrative services in the most cost effective manner possible.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Research Program Projects (P01)
Project #
2P01GM067166-06A1
Application #
7690609
Study Section
Special Emphasis Panel (ZRG1-CB-L (40))
Project Start
2009-09-15
Project End
2014-08-31
Budget Start
2009-09-15
Budget End
2010-08-31
Support Year
6
Fiscal Year
2009
Total Cost
$64,780
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Jayakanthan, Samuel; Braiterman, Lelita T; Hasan, Nesrin M et al. (2017) Human copper transporter ATP7B (Wilson disease protein) forms stable dimers in vitro and in cells. J Biol Chem 292:18760-18774
Hamilton, James P; Koganti, Lahari; Muchenditsi, Abigael et al. (2016) Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice. Hepatology 63:1828-41
Gupta, Arnab; Schell, Michael J; Bhattacharjee, Ashima et al. (2016) Myosin Vb mediates Cu+ export in polarized hepatocytes. J Cell Sci 129:1179-89
Krishnamoorthy, Lakshmi; Cotruvo Jr, Joseph A; Chan, Jefferson et al. (2016) Copper regulates cyclic-AMP-dependent lipolysis. Nat Chem Biol 12:586-92
Kline, Chelsey D; Gambill, Benjamin F; Mayfield, Mary et al. (2016) pH-regulated metal-ligand switching in the HM loop of ATP7A: a new paradigm for metal transfer chemistry. Metallomics 8:729-33
Clifford, Rebecca J; Maryon, Edward B; Kaplan, Jack H (2016) Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu? uptake system. J Cell Sci 129:1711-21
Dmitriev, Oleg Y; Lutsenko, Svetlana; Muyldermans, Serge (2016) Nanobodies as Probes for Protein Dynamics in Vitro and in Cells. J Biol Chem 291:3767-75
Braiterman, Lelita T; Gupta, Arnab; Chaerkady, Raghothama et al. (2015) Communication between the N and C termini is required for copper-stimulated Ser/Thr phosphorylation of Cu(I)-ATPase (ATP7B). J Biol Chem 290:8803-19
Huang, Yiping; Nokhrin, Sergiy; Hassanzadeh-Ghassabeh, Gholamreza et al. (2014) Interactions between metal-binding domains modulate intracellular targeting of Cu(I)-ATPase ATP7B, as revealed by nanobody binding. J Biol Chem 289:32682-93
Nyasae, Lydia K; Schell, Michael J; Hubbard, Ann L (2014) Copper directs ATP7B to the apical domain of hepatic cells via basolateral endosomes. Traffic 15:1344-65

Showing the most recent 10 out of 67 publications