This resubmission of a Revision (formerly Competing Supplementary) application seeks support to augment the currently funded POI grant POI HD 025995, """"""""Stimulus Control in Mental Retardation."""""""" Three of the currently funded projects are evaluating response to visual stimuli in individuals with intellectual disabilities: Projects 1&2 study stimulus structure variables and variation in stimulus features such as color and form that may be important in promoting desirable forms of stimulus control in functional academics and augmentative/alternative communication (AAC), respectively. Project 3 studies stimulus control processes in the detection of facial expression and emotion by persons from various disability groups. The proposed Project 5 will expand the scope of the current research program to address the problem of stimulus over-selectivity as it may impact stimulus control in functional academics, augmentative/alternative communication, and face processing. Overselectivity refers to maladaptive narrow attending that is a common learning problem in children with intellectual disabilities. Overselectivity is often associated with autism spectrum disorders (ASD), but the research foundation for this relation is based largely on simple discrimination learning procedures that fail to capture the complex relational learning aspects of special-education curricula. Research at the Shriver Center and elsewhere has produced methodologies to study overselectivity in contexts that model teaching situations. We have also developed an approach toward remediation that incorporates differential observing response (DOR) procedures;this approach can eliminate the problem by corrective therapy for some individuals and by behavioral prosthesis for others. Project 5 proposes a formal comparison of stimulus overselectivity in the four study populations of the ongoing program project: MA- and CA-matched children with ASD, Down syndrome, &intellectual disabilities of mixed/unknown etiology;and MA-matched typically developing children. Stimulus sets of clinical/educational interest will parallel those of the existing POI projects (AAC icons, photos of faces). We will determine whether an ASD diagnosis is related to (1) increased prevalence or severity of overselective stimulus control;and (2) the effectiveness, durability, and net gain resulting from intervention with DOR procedures and remedial training. We also propose a series of applied studies to examine generalization and durability of DOR interventions in special-education classrooms. The results will enhance the applications potential of the other projects and contribute to a better characterization of the learning problems associated with the study populations.

Public Health Relevance

The proposed research is highly relevant to the public health interests of NICHD and its Mental Retardation Developmental Disabilities branch because it will contribute to the improvement of evaluation and teaching methods for individuals with autism and other neurodevelopmental or intellectual disabilities. Specific areas of application include improvements in functional communication capabilities for children with moderate to severe disabilities.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
3P01HD025995-20S1A2
Application #
7943326
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Kau, Alice S
Project Start
1997-05-01
Project End
2012-07-31
Budget Start
2010-09-20
Budget End
2011-07-31
Support Year
20
Fiscal Year
2010
Total Cost
$133,323
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Pediatrics
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
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Dube, William V; Farber, Rachel S; Mueller, Marlana R et al. (2016) Stimulus Overselectivity in Autism, Down Syndrome, and Typical Development. Am J Intellect Dev Disabil 121:219-35
McIlvane, W J; Gerard, C J; Kledaras, J B et al. (2016) Teaching Stimulus-Stimulus Relations to Minimally Verbal Individuals: Reflections on Technology and Future Directions. Eur J Behav Anal 17:49-68
Morro, Greg; Mackay, Harry A; Carlin, Michael T (2014) Rapid Teaching of Arbitrary Matching in Individuals with Intellectual Disabilities. Psychol Rec 64:731-742
Wilkinson, Krista M; O'Neill, Tara; McIlvane, William J (2014) Eye-tracking measures reveal how changes in the design of aided AAC displays influence the efficiency of locating symbols by school-age children without disabilities. J Speech Lang Hear Res 57:455-66
Dube, William V; Wilkinson, Krista M (2014) The potential influence of stimulus overselectivity in AAC: information from eye tracking and behavioral studies of attention with individuals with intellectual disabilities. Augment Altern Commun 30:172-85
Wilkinson, Krista M; Mitchell, Teresa (2014) Eye tracking research to answer questions about augmentative and alternative communication assessment and intervention. Augment Altern Commun 30:106-19
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Wilkinson, Krista M; McIlvane, William J (2013) Perceptual factors influence visual search for meaningful symbols in individuals with intellectual disabilities and Down syndrome or autism spectrum disorders. Am J Intellect Dev Disabil 118:353-64
McIlvane, William J; Kledaras, Joanne B (2012) Some Things We Learned from Sidman and Some We Did Not (We Think). Eur J Behav Anal 13:97-109

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