The Administrative/Statistical Services Core has three main functions: to facilitate scientific and administrative communication among the Project participants, to manage the central data archives and facilitate exchange of data among projects, and to coordinate statistical services and consultation for the participating investigators. Specifically, it will provide and maintain resources for data management and analysis, serving the three projects and their interactions. The P.I. will supervise the Administrative, Statistical and Computer interactions. In addition, it has primary responsibility for planning, implementation and overall coordination of the interface between the Cores and the five projects. A central database will be constructed to include the following data partitions: Genetic Probe results, Cell Line samples, Cytoarchitectonic measurements, Event Related Potential and Magnetic Resonance Imaging results and aggregated Neurobehavioral measures. Database connectivity is available via a fiber optic link to the University of California, San Diego Super Computer Center, from which satellite bandwidth provides access to each investigator connected to the Internet this Core A has primary responsibility for database maintenance and construction including security precautions and data entry verification.

Project Start
1999-03-01
Project End
2000-02-29
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
4
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Chailangkarn, Thanathom; Noree, Chalongrat; Muotri, Alysson R (2018) The contribution of GTF2I haploinsufficiency to Williams syndrome. Mol Cell Probes 40:45-51
Ng, Rowena; Lai, Philip; Brown, Timothy T et al. (2018) Neuroanatomical correlates of emotion-processing in children with unilateral brain lesion: A preliminary study of limbic system organization. Soc Neurosci 13:688-700
Griesi-Oliveira, Karina; Suzuki, Angela May; Muotri, Alysson Renato (2017) TRPC Channels and Mental Disorders. Adv Exp Med Biol 976:137-148
Herai, Roberto H; Negraes, Priscilla D; Muotri, Alysson R (2017) Evidence of nuclei-encoded spliceosome mediating splicing of mitochondrial RNA. Hum Mol Genet 26:2472-2479
Ng, Rowena; Brown, Timothy T; Järvinen, Anna M et al. (2016) Structural integrity of the limbic-prefrontal connection: Neuropathological correlates of anxiety in Williams syndrome. Soc Neurosci 11:187-92
Ng, Rowena; Brown, Timothy T; Erhart, Matthew et al. (2016) Morphological differences in the mirror neuron system in Williams syndrome. Soc Neurosci 11:277-88
Green, Tamar; Fierro, Kyle C; Raman, Mira M et al. (2016) Surface-based morphometry reveals distinct cortical thickness and surface area profiles in Williams syndrome. Am J Med Genet B Neuropsychiatr Genet 171B:402-13
Järvinen, Anna; Ng, Rowena; Crivelli, Davide et al. (2015) Relations between social-perceptual ability in multi- and unisensory contexts, autonomic reactivity, and social functioning in individuals with Williams syndrome. Neuropsychologia 73:127-40
Järvinen, Anna; Ng, Rowena; Bellugi, Ursula (2015) Autonomic response to approachability characteristics, approach behavior, and social functioning in Williams syndrome. Neuropsychologia 78:159-70
Ng, Rowena; Fishman, Inna; Bellugi, Ursula (2015) Frontal asymmetry index in Williams syndrome: Evidence for altered emotional brain circuitry? Soc Neurosci 10:366-75

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