The objective of Core A is indicated by its title. Its functions are defined as the provision of technologies, services and research materials used by multiple Research Components, which are difficult or expensive to generate, which can be provided by a central source, and indeed would be ridiculously wasteful for each lab to provide for itself. The emphasis here is on high technology aspects, and materials that require special facilities or know-how to generate.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD037105-12
Application #
8092702
Study Section
Special Emphasis Panel (ZHD1)
Project Start
2010-06-01
Project End
2014-05-31
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
12
Fiscal Year
2010
Total Cost
$300,027
Indirect Cost
Name
California Institute of Technology
Department
Type
DUNS #
009584210
City
Pasadena
State
CA
Country
United States
Zip Code
91125
Slota, Leslie A; McClay, David R (2018) Identification of neural transcription factors required for the differentiation of three neuronal subtypes in the sea urchin embryo. Dev Biol 435:138-149
Hutchins, Erica J; Kunttas, Ezgi; Piacentino, Michael L et al. (2018) Migration and diversification of the vagal neural crest. Dev Biol :
Kerosuo, Laura; Neppala, Pushpa; Hsin, Jenny et al. (2018) Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma. Proc Natl Acad Sci U S A 115:E7351-E7360
Rogers, Crystal D; Sorrells, Lisa K; Bronner, Marianne E (2018) A catenin-dependent balance between N-cadherin and E-cadherin controls neuroectodermal cell fate choices. Mech Dev 152:44-56
McClay, David R; Miranda, Esther; Feinberg, Stacy L (2018) Neurogenesis in the sea urchin embryo is initiated uniquely in three domains. Development 145:
Roellig, Daniela; Tan-Cabugao, Johanna; Esaian, Sevan et al. (2017) Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells. Elife 6:
Lignell, Antti; Kerosuo, Laura; Streichan, Sebastian J et al. (2017) Identification of a neural crest stem cell niche by Spatial Genomic Analysis. Nat Commun 8:1830
Martik, Megan L; McClay, David R (2017) New insights from a high-resolution look at gastrulation in the sea urchin, Lytechinus variegatus. Mech Dev 148:3-10
Murko, Christina; Bronner, Marianne E (2017) Tissue specific regulation of the chick Sox10E1 enhancer by different Sox family members. Dev Biol 422:47-57
Peter, Isabelle S (2017) Regulatory states in the developmental control of gene expression. Brief Funct Genomics 16:281-287

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