The objective of the Biostatistics and Data Management Core is to provide comprehensive biostatistical support to the Program Project grant """"""""Prenatal Programming of Reproductive Health and Disease"""""""". The Core will: 1) provide assistance with the design of each study; 2) perform the data analysis; 3) develop statistical methods that enhance the ability to analyze the data from these experiments; and ensure study outcomes are analyzed correctly before being published.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD044232-05
Application #
7668720
Study Section
Special Emphasis Panel (ZHD1)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
5
Fiscal Year
2008
Total Cost
$49,895
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Puttabyatappa, Muraly; Irwin, Ashleigh; Martin, Jacob D et al. (2018) Developmental Programming: Gestational Exposure to Excess Testosterone Alters Expression of Ovarian Matrix Metalloproteases and Their Target Proteins. Reprod Sci 25:882-892
Puttabyatappa, Muraly; Padmanabhan, Vasantha (2018) Ovarian and Extra-Ovarian Mediators in the Development of Polycystic Ovary Syndrome. J Mol Endocrinol 61:R161-R184
Puttabyatappa, Muraly; Lu, Chunxia; Martin, Jacob D et al. (2018) Developmental Programming: Impact of Prenatal Testosterone Excess on Steroidal Machinery and Cell Differentiation Markers in Visceral Adipocytes of Female Sheep. Reprod Sci 25:1010-1023
Puttabyatappa, Muraly; Padmanabhan, Vasantha (2018) Developmental Programming of Ovarian Functions and Dysfunctions. Vitam Horm 107:377-422
Puttabyatappa, Muraly; Andriessen, Victoria; Mesquitta, Makeda et al. (2017) Developmental Programming: Impact of Gestational Steroid and Metabolic Milieus on Mediators of Insulin Sensitivity in Prenatal Testosterone-Treated Female Sheep. Endocrinology 158:2783-2798
Puttabyatappa, Muraly; Padmanabhan, Vasantha (2017) Prenatal Testosterone Programming of Insulin Resistance in theĀ Female Sheep. Adv Exp Med Biol 1043:575-596
Hakim, Christopher; Padmanabhan, Vasantha; Vyas, Arpita K (2017) Gestational Hyperandrogenism in Developmental Programming. Endocrinology 158:199-212
Recabarren, S E; Recabarren, M; Sandoval, D et al. (2017) Puberty arises with testicular alterations and defective AMH expression in rams prenatally exposed to testosterone. Domest Anim Endocrinol 61:100-107
Veiga-Lopez, A; Moeller, J; Abbott, D H et al. (2016) Developmental programming: rescuing disruptions in preovulatory follicle growth and steroidogenesis from prenatal testosterone disruption. J Ovarian Res 9:39
Vyas, Arpita K; Hoang, Vanessa; Padmanabhan, Vasantha et al. (2016) Prenatal programming: adverse cardiac programming by gestational testosterone excess. Sci Rep 6:28335

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