Abstract

The advantage of the Reproductive Immunology Core Unit will be to centralize a number of techniques and services that are pivotal to all of the Program's projects. Through this, the Program will prove cost effective by saving significant funds with the bulk purchasing of tissue culture and other consumable components, as well as animal housing. The ability to consolidate this Core's purchasing will enable us to ask for tenders from individual companies who will be able to supply the majority of items needed. This method will lead to expected savings of at least 50%. In addition, the establishment of standing orders will streamline both ordering and receiving of products. Dr Abrahams and Dr Mor will meet regularly to ensure the efficient and cost-effective service of this Core Unit.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program Projects (P01)
Project #
5P01HD054713-04
Application #
8378434
Study Section
Special Emphasis Panel (ZHD1-MCHG-B)
Project Start
Project End
Budget Start
2012-06-01
Budget End
2013-05-31
Support Year
4
Fiscal Year
2012
Total Cost
$208,400
Indirect Cost
$83,433

  Institution

Name
Yale University
Department
Type
DUNS #
043207562
City
New Haven
State
CT
Country
United States
Zip Code
06520

  Publications

Kwon, Ja-Young; Aldo, Paulomi; You, Yuan et al. (2018) Relevance of placental type I interferon beta regulation for pregnancy success. Cell Mol Immunol 15:1010-1026
Racicot, Karen; Kwon, Ja Young; Aldo, Paulomi et al. (2016) Type I Interferon Regulates the Placental Inflammatory Response to Bacteria and is Targeted by Virus: Mechanism of Polymicrobial Infection-Induced Preterm Birth. Am J Reprod Immunol 75:451-60
Mhatre, Mohak V; Potter, Julie A; Lockwood, Charles J et al. (2016) Thrombin Augments LPS-Induced Human Endometrial Endothelial Cell Inflammation via PAR1 Activation. Am J Reprod Immunol 76:29-37
Silasi, Michelle; Cardenas, Ingrid; Kwon, Ja-Young et al. (2015) Viral infections during pregnancy. Am J Reprod Immunol 73:199-213
Norwitz, Errol R; Bonney, Elizabeth A; Snegovskikh, Victoria V et al. (2015) Molecular Regulation of Parturition: The Role of the Decidual Clock. Cold Spring Harb Perspect Med 5:
Mor, Gil; Kwon, Ja-Young (2015) Trophoblast-microbiome interaction: a new paradigm on immune regulation. Am J Obstet Gynecol 213:S131-7
Young, Omar M; Tang, Zhonghua; Niven-Fairchild, Tracy et al. (2015) Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. Am J Reprod Immunol 73:22-35
Aldo, Paulomi B; Racicot, Karen; Craviero, Vinicius et al. (2014) Trophoblast induces monocyte differentiation into CD14+/CD16+ macrophages. Am J Reprod Immunol 72:270-84
Racicot, Karen E; Wünsche, Vera; Auerbach, Ben et al. (2014) Human chorionic gonadotropin enhances trophoblast-epithelial interaction in an in vitro model of human implantation. Reprod Sci 21:1274-80
Hoang, Mai; Potter, Julie A; Gysler, Stefan M et al. (2014) Human fetal membranes generate distinct cytokine profiles in response to bacterial Toll-like receptor and nod-like receptor agonists. Biol Reprod 90:39

Showing the most recent 10 out of 46 publications