Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL006296-36
Application #
5213063
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
36
Fiscal Year
1996
Total Cost
Indirect Cost
Chang, Audrey N; Battiprolu, Pavan K; Cowley, Patrick M et al. (2015) Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo. J Biol Chem 290:10703-16
Thomas, Gail D (2015) Functional sympatholysis in hypertension. Auton Neurosci 188:64-8
Martin, Elizabeth A; Barresi, Rita; Byrne, Barry J et al. (2012) Tadalafil alleviates muscle ischemia in patients with Becker muscular dystrophy. Sci Transl Med 4:162ra155
Fadel, Paul J; Farias Iii, Martin; Gallagher, Kevin M et al. (2012) Oxidative stress and enhanced sympathetic vasoconstriction in contracting muscles of nitrate-tolerant rats and humans. J Physiol 590:395-407
Stull, James T; Kamm, Kristine E; Vandenboom, Rene (2011) Myosin light chain kinase and the role of myosin light chain phosphorylation in skeletal muscle. Arch Biochem Biophys 510:120-8
Sachan, Nita; Dey, Asim; Rotter, David et al. (2011) Sustained hemodynamic stress disrupts normal circadian rhythms in calcineurin-dependent signaling and protein phosphorylation in the heart. Circ Res 108:437-45
Massare, Jorge; Berry, Jeff M; Luo, Xiang et al. (2010) Diminished cardiac fibrosis in heart failure is associated with altered ventricular arrhythmia phenotype. J Cardiovasc Electrophysiol 21:1031-7
Tandan, Samvit; Wang, Yanggan; Wang, Thomas T et al. (2009) Physical and functional interaction between calcineurin and the cardiac L-type Ca2+ channel. Circ Res 105:51-60
Huang, Jian; Shelton, John M; Richardson, James A et al. (2008) Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy. J Biol Chem 283:19748-56
Tannous, Paul; Zhu, Hongxin; Nemchenko, Andriy et al. (2008) Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy. Circulation 117:3070-8

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