Rationale and Procedures The administrative structure of the Program Project Grant and the responsibilities and the duties of the Program Director, have been outlined under Organization and Administrative Structure. Briefly, these include: 1. Scientific Responsibilities a. Scientific integration, coordination and direction of research projects. b. Encouraging and supporting exploration of new avenues of research and phasing out unpromising research. c. Recruitment of new investigators with promising expertise and direction for future projects. d. Consultation with internal advisors and external consultants concerning importance and progress of the research. e. Preparation of scientific progress reports and renewal applications. f. Planning scientific work-in-progress sessions, special seminars and symposia. The Director is aided in these functions primarily by the Co-Director and the members of the Advisory and Executive Committees. 2. Administrative Responsibilities a. Following NIH guidelines for Program Project Grant support. b. Allocation of budgets in accordance with NIH policies, recommendations and scientific productivity of projects. c. Careful justification of expenditures, exploration of more economical or efficient ways of using resources, equipment, and supplies. d. Aiding investigators in projecting expenditures and reporting monthly on expenditures and balance. e. Allocation of travel funds among investigators and research associates in an equitable and fair manner. f. Preparing annual budgets and projections. g. Circulation of announcements of important events related to the Program. h. Keeping departmental chairs whose members participate in the Program informed of developments, effort, contributions, and salary support. i. Informing the Dean of progress, scientific direction, administrative problems and future plans. j . Holding regular meetings of the Executive Committee. The Director is assisted in these responsibilities by the Co-Director, the Administrator and Secretary. 3. Administrative Assistance: The Contract Administrator of the Cardiovascular Center, Lori Bassler, will assist the Director, Dr. Abboud, in day-to-day administrative matters such as purchasing, preparations of monthly financial statements and implementation of administrative decisions. The administrative matters are considerable and Mrs. Bassler has extensive experience in the administration of large grants. 4. Centralization of Certain Budgetary Items The primary reasons are economy and efficiency. Secretarial Support: There are no secretaries listed on individual budgets. The major administrative responsibilities are in the Director's office and a large part of the scientific output is from the Cardiovascular Center and the Department of Medicine. Secretarial support is requested for this effort

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL014388-45
Application #
9482444
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Program Officer
Maric-Bilkan, Christine
Project Start
Project End
Budget Start
2018-06-01
Budget End
2019-05-31
Support Year
45
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Iowa
Department
Type
DUNS #
062761671
City
Iowa City
State
IA
Country
United States
Zip Code
52242
Zhang, Yu-Ping; Huo, Yan-Li; Fang, Zhi-Qin et al. (2018) Maternal high-fat diet acts on the brain to induce baroreflex dysfunction and sensitization of angiotensin II-induced hypertension in adult offspring. Am J Physiol Heart Circ Physiol 314:H1061-H1069
Johnson, Casey P; Christensen, Gary E; Fiedorowicz, Jess G et al. (2018) Alterations of the cerebellum and basal ganglia in bipolar disorder mood states detected by quantitative T1? mapping. Bipolar Disord 20:381-390
Hardy, Rachel N; Simsek, Zinar D; Curry, Brandon et al. (2018) Aging affects isoproterenol-induced water drinking, astrocyte density, and central neuronal activation in female Brown Norway rats. Physiol Behav 192:90-97
Lane-Cordova, Abbi D; Kalil, Graziela Z; Wagner, Christopher J et al. (2018) Hemoglobin A1c and C-reactive protein are independently associated with blunted nocturnal blood pressure dipping in obesity-related prediabetes. Hypertens Res 41:33-38
Larson, Robert A; Chapleau, Mark W (2018) Increased cardiac sympathetic activity: Cause or compensation in vasovagal syncope? Clin Auton Res 28:265-266
Tong, Brian; Abosi, Oluchi; Schmitz, Samantha et al. (2018) Bipolar disorder and related mood states are not associated with endothelial function of small arteries in adults without heart disease. Gen Hosp Psychiatry 51:36-40
Zeng, Wei-Zheng; Marshall, Kara L; Min, Soohong et al. (2018) PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex. Science 362:464-467
DuBose, Lyndsey E; Boles Ponto, Laura L; Moser, David J et al. (2018) Higher Aortic Stiffness Is Associated With Lower Global Cerebrovascular Reserve Among Older Humans. Hypertension 72:476-482
Holwerda, Seth W; Luehrs, Rachel E; Gremaud, Allene L et al. (2018) Relative burst amplitude of muscle sympathetic nerve activity is an indicator of altered sympathetic outflow in chronic anxiety. J Neurophysiol 120:11-22
Sabharwal, Rasna; Mason, Bianca N; Kuburas, Adisa et al. (2018) Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension. J Cereb Blood Flow Metab :271678X17751352

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