Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL022619-23
Application #
6457661
Study Section
Project Start
2001-07-01
Project End
2002-06-30
Budget Start
Budget End
Support Year
23
Fiscal Year
2001
Total Cost
$142,461
Indirect Cost
Name
University of Cincinnati
Department
Type
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Jagatheesan, Ganapathy; Rajan, Sudarsan; Wieczorek, David F (2010) Investigations into tropomyosin function using mouse models. J Mol Cell Cardiol 48:893-8
Fuller-Bicer, Geraldine A; Varadi, Gyula; Koch, Sheryl E et al. (2009) Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit. Am J Physiol Heart Circ Physiol 297:H117-24
Sadayappan, Sakthivel; Finley, Natosha; Howarth, Jack W et al. (2008) Role of the acidic N'region of cardiac troponin I in regulating myocardial function. FASEB J 22:1246-57
Pattison, James Scott; Waggoner, Jason R; James, Jeanne et al. (2008) Phospholamban overexpression in transgenic rabbits. Transgenic Res 17:157-70
Jagatheesan, Ganapathy; Rajan, Sudarsan; Petrashevskaya, Natalia et al. (2007) Rescue of tropomyosin-induced familial hypertrophic cardiomyopathy mice by transgenesis. Am J Physiol Heart Circ Physiol 293:H949-58
Scragg, Jason L; Fearon, Ian M; Boyle, John P et al. (2005) Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels. FASEB J 19:150-2
Rubio, Marta; Bodi, Ilona; Fuller-Bicer, Geraldine A et al. (2005) Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis. J Cardiovasc Pharmacol Ther 10:235-49
Bodi, Ilona; Mikala, Gabor; Koch, Sheryl E et al. (2005) The L-type calcium channel in the heart: the beat goes on. J Clin Invest 115:3306-17
Jagatheesan, Ganapathy; Rajan, Sudarsan; Petrashevskaya, Natalia et al. (2004) Physiological significance of troponin T binding domains in striated muscle tropomyosin. Am J Physiol Heart Circ Physiol 287:H1484-94
Matthes, Jan; Jager, Andreas; Handrock, Renate et al. (2004) Ca2+-dependent modulation of single human cardiac L-type calcium channels by the calcineurin inhibitor cyclosporine. J Mol Cell Cardiol 36:241-55

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