Abstract

Core Unit C is responsible for maintaining the pedigreed baboon colony, managing the breeding groups, and conducting the experimental procedures using baboons. Colony maintenance includes daily care, i.e., feeding assigned diets, cleaning cages observing animals for signs of illness, treating sick animals, and maintaining animal database records. Breeding colony management includes maintaining sire-dam assignments, monitoring dams for pregnancies recording births in the animal database, and culling unproductive animals from the colony. Experimental procedures include the dual dietary challenge, adiposity measurements by bioimpedance, and biopsy of core adipose tissue. Animal caretakers are responsible for animal maintenance on a daily basis of experimental; diet preparation. Veterinary technicians provide health care and are responsible for experimental procedures.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL028972-18
Application #
6302160
Study Section
Project Start
2000-01-01
Project End
2000-12-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
18
Fiscal Year
2000
Total Cost
$426,318
Indirect Cost

  Institution

Name
Southwest Foundation for Biomedical Research
Department
Type
DUNS #
City
San Antonio
State
TX
Country
United States
Zip Code
78245

  Publications

Mahaney, Michael C; Karere, Genesio M; Rainwater, David L et al. (2018) Diet-induced early-stage atherosclerosis in baboons: Lipoproteins, atherogenesis, and arterial compliance. J Med Primatol 47:3-17
Joganic, Jessica L; Willmore, Katherine E; Richtsmeier, Joan T et al. (2018) Additive genetic variation in the craniofacial skeleton of baboons (genus Papio) and its relationship to body and cranial size. Am J Phys Anthropol 165:269-285
Eichel, Kaleigh Anne; Ackermann, Rebecca Rogers (2016) Variation in the nasal cavity of baboon hybrids with implications for late Pleistocene hominins. J Hum Evol 94:134-45
Tiyasatkulkovit, Wacharaporn; Malaivijitnond, Suchinda; Charoenphandhu, Narattaphol et al. (2014) Pueraria mirifica extract and puerarin enhance proliferation and expression of alkaline phosphatase and type I collagen in primary baboon osteoblasts. Phytomedicine 21:1498-503
Chen, Shuyuan; Bastarrachea, Raul A; Roberts, Brad J et al. (2014) Successful ? cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1. Cell Cycle 13:1145-51
Higgins, Paul B; Rodriguez, Perla J; Voruganti, V Saroja et al. (2014) Body composition and cardiometabolic disease risk factors in captive baboons (Papio hamadryas sp.): sexual dimorphism. Am J Phys Anthropol 153:9-14
Karere, Genesio M; Glenn, Jeremy P; Birnbaum, Shifra et al. (2013) Identification of candidate genes encoding an LDL-C QTL in baboons. J Lipid Res 54:1776-85
Shi, Qiang; Hodara, Vida; Simerly, Calvin R et al. (2013) Ex vivo reconstitution of arterial endothelium by embryonic stem cell-derived endothelial progenitor cells in baboons. Stem Cells Dev 22:631-42
Shi, Qiang; Schatten, Gerald; Hodara, Vida et al. (2013) Endothelial reconstitution by CD34+ progenitors derived from baboon embryonic stem cells. J Cell Mol Med 17:242-51
Rodríguez-Sánchez, I P; Garza-Rodríguez, M L; Mohamed-Noriega, K et al. (2013) Olfactomedin-like 3 (OLFML3) gene expression in baboon and human ocular tissues: cornea, lens, uvea, and retina. J Med Primatol 42:105-11

Showing the most recent 10 out of 291 publications