Abstract

This is a request for renewal of Program-Project Grant AM 06704, which has supported research in our Neuroendocrine Laboratory since 1962. The laboratory is a confederation of core investigators, most of whom are based in the Department of Physiology, University of California, San Francisco. They collaborate with various scientists in other departments and other institutions. The research is concerned with the interactions between the nervous and the endocrine systems. The primary goal of the program is elucidation of the neural and humoral mechanisms regulating endocrine function. A complete numbered bibliography of papers from this laboratory that were published in the report period is included in the comprehensive progress report, followed by a list of other papers cited in the application. References in the text to the former are by number and to the latter are by name and date.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL029714-23
Application #
3098150
Study Section
Heart, Lung, and Blood Research Review Committee B (HLBB)
Project Start
1978-07-01
Project End
1988-06-30
Budget Start
1985-07-01
Budget End
1986-06-30
Support Year
23
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Murakami, K; Akana, S F; Dallman, M F (1997) Dopamine-beta-hydroxylase activity is necessary for hypothalamo-pituitary-adrenal (HPA) responses to ether, and stress-induced facilitation of subsequent HPA responses to acute ether emerges as HPA responses are inhibited by increasing corticosterone (B). J Neuroendocrinol 9:601-8
Chiu, T; Reid, I A (1996) Role of cyclic GMP-inhibitable phosphodiesterase and nitric oxide in the beta adrenoceptor control of renin secretion. J Pharmacol Exp Ther 278:793-9
Chiu, T; Reid, I A (1995) Effect of inhibition of nitric oxide synthesis on the cardiovascular and endocrine responses to hemorrhage in conscious rabbits. Hypertens Res 18:55-61
Reid, I A; Chou, L (1995) Effect of blockade of nitric oxide synthesis on the renin secretory response to frusemide in conscious rabbits. Clin Sci (Lond) 88:657-63
Ganong, W F (1995) Reproduction and the renin-angiotensin system. Neurosci Biobehav Rev 19:241-50
Tkacs, N C; Strack, A M (1995) Systemic endotoxin induces Fos-like immunoreactivity in rat spinal sympathetic regions. J Auton Nerv Syst 51:1-7
Shiotsu, T; Yamamoto, A; Kagawa, S et al. (1995) Effect of moderately increased intrapelvic pressure on renal tissue pressure and vasopressin release in rabbits. Hypertens Res 18:197-202
Quillen Jr, E W; Reid, I A (1995) Intravertebral ANG II effects on plasma renin and Na excretion in dogs at constant renal artery pressure. Am J Physiol 268:F296-301
Goyer, M; Bui, H; Chou, L et al. (1994) Effect of inhibition of nitric oxide synthesis on vasopressin secretion in conscious rabbits. Am J Physiol 266:H822-8
Kumagai, K; Reid, I A (1994) Losartan inhibits sympathetic and cardiovascular responses to carotid occlusion. Hypertension 23:827-31

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