Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL030616-03
Application #
4696107
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Rochester
Department
Type
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Sahni, Abha; Arévalo, Maria T; Sahni, Sanjeev K et al. (2009) The VE-cadherin binding domain of fibrinogen induces endothelial barrier permeability and enhances transendothelial migration of malignant breast epithelial cells. Int J Cancer 125:577-84
Sahni, Sanjeev K; Rydkina, Elena (2009) Host-cell interactions with pathogenic Rickettsia species. Future Microbiol 4:323-39
Sahni, Sanjeev K; Rydkina, Elena; Sahni, Abha (2008) The proteasome inhibitor MG132 induces nuclear translocation of erythroid transcription factor Nrf2 and cyclooxygenase-2 expression in human vascular endothelial cells. Thromb Res 122:820-5
Sahni, A; Simpson-Haidaris, P J; Sahni, S K et al. (2008) Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2). J Thromb Haemost 6:176-83
Mosesson, M W; Hernandez, I; Raife, T J et al. (2007) Plasma fibrinogen gamma'chain content in the thrombotic microangiopathy syndrome. J Thromb Haemost 5:62-9
Rydkina, Elena; Sahni, Abha; Baggs, Raymond B et al. (2006) Infection of human endothelial cells with spotted Fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins. Infect Immun 74:5067-74
Sahni, Abha; Khorana, Alok A; Baggs, Raymond B et al. (2006) FGF-2 binding to fibrin(ogen) is required for augmented angiogenesis. Blood 107:126-31
Duan, Hai Ou; Simpson-Haidaris, Patricia J (2006) Cell type-specific differential induction of the human gamma-fibrinogen promoter by interleukin-6. J Biol Chem 281:12451-7
Fay, Philip J; Jenkins, P Vincent (2005) Mutating factor VIII: lessons from structure to function. Blood Rev 19:15-27
Clifton, Dawn R; Rydkina, Elena; Huyck, Heidie et al. (2005) Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB. Int J Med Microbiol 295:267-78

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