Abstract

The sub projects have in common the need for enzymes, cultures of neonatal cardiac myocytes and non myocytes, and preparation of recombinant baculoviruses and replication-defective adenoviruses whose preparations are well-established but require technical expertise and are time-intensive. It is most efficient and cost-effective to prepare these materials in a common core facility when they are administered and supervised by research scientists with appropriate expertise.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL036573-12
Application #
6109832
Study Section
Project Start
1999-03-01
Project End
2000-02-29
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
12
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
University of Toledo
Department
Type
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614

  Publications

Duan, Qiming; Xu, Yunhui; Marck, Pauline V et al. (2018) Preconditioning and Postconditioning by Cardiac Glycosides in the Mouse Heart. J Cardiovasc Pharmacol 71:95-103
Duan, Qiming; Xu, Yunhui; Marck, Pauline et al. (2017) Pre- and Post-conditioning by Cardiac Glycosides in the Mouse Heart. J Cardiovasc Pharmacol :
Morrill, Gene A; Kostellow, Adele B; Liu, Lijun et al. (2016) Evolution of the ?-Subunit of Na/K-ATPase from Paramecium to Homo sapiens: Invariance of Transmembrane Helix Topology. J Mol Evol 82:183-98
Wu, Jian; Li, Daxiang; Du, Lingling et al. (2015) Ouabain prevents pathological cardiac hypertrophy and heart failure through activation of phosphoinositide 3-kinase ? in mouse. Cell Biosci 5:64
Duan, Qiming; Madan, Namrata D; Wu, Jian et al. (2015) Role of phosphoinositide 3-kinase IA (PI3K-IA) activation in cardioprotection induced by ouabain preconditioning. J Mol Cell Cardiol 80:114-25
Mehta, Gaurav; Kumarasamy, Sivarajan; Wu, Jian et al. (2015) MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy. J Mol Cell Cardiol 88:101-10
Akkuratov, Evgeny E; Wu, Jian; Sowa, David et al. (2015) Ouabain-Induced Signaling and Cell Survival in SK-N-SH Neuroblastoma Cells Differentiated by Retinoic Acid. CNS Neurol Disord Drug Targets 14:1343-9
Li, Caixia; Culver, Silas A; Quadri, Syed et al. (2015) High-fat diet amplifies renal renin angiotensin system expression, blood pressure elevation, and renal dysfunction caused by Ceacam1 null deletion. Am J Physiol Endocrinol Metab 309:E802-10
Balasubramanian, Priya; Varde, Pratibha A; Abdallah, Simon Labib et al. (2015) Differential effects of prenatal stress on metabolic programming in diet-induced obese and dietary-resistant rats. Am J Physiol Endocrinol Metab 309:E582-8
Gable, Marjorie E; Abdallah, Simon L; Najjar, Sonia M et al. (2014) Digitalis-induced cell signaling by the sodium pump: on the relation of Src to Na(+)/K(+)-ATPase. Biochem Biophys Res Commun 446:1151-4

Showing the most recent 10 out of 247 publications