Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL038079-04
Application #
3880506
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
George Washington University
Department
Type
DUNS #
City
Washington
State
DC
Country
United States
Zip Code
20052
Mak, I T; Weglicki, W B (1994) Antioxidant activity of calcium channel blocking drugs. Methods Enzymol 234:620-30
Bean, B L; Varghese, P J (1994) Role of dietary magnesium deficiency in the pressor and arrhythmogenic response to epinephrine in the intact dog. Am Heart J 127:96-102
Weglicki, W B; Mak, I T; Stafford, R E et al. (1994) Neurogenic peptides and the cardiomyopathy of magnesium-deficiency: effects of substance P-receptor inhibition. Mol Cell Biochem 130:103-9
Mak, I T; Stafford, R; Weglicki, W B (1994) Loss of red blood cell glutathione during Mg deficiency: prevention by vitamin E, D-propranolol, and chloroquine. Am J Physiol 267:C1366-70
Weglicki, W B; Stafford, R E; Freedman, A M et al. (1993) Modulation of cytokines and myocardial lesions by vitamin E and chloroquine in a Mg-deficient rat model. Am J Physiol 264:C723-6
Tortolani, A J; Powell, S R; Misik, V et al. (1993) Detection of alkoxyl and carbon-centered free radicals in coronary sinus blood from patients undergoing elective cardioplegia. Free Radic Biol Med 14:421-6
Weglicki, W B; Stafford, R E; Dickens, B F et al. (1993) Inhibition of tumor necrosis factor-alpha by thalidomide in magnesium deficiency. Mol Cell Biochem 129:195-200
Freedman, A M; Mak, I T; Stafford, R E et al. (1992) Erythrocytes from magnesium-deficient hamsters display an enhanced susceptibility to oxidative stress. Am J Physiol 262:C1371-5
Weglicki, W B; Mak, I T; Dickens, B F et al. (1992) Beta-blockers, calcium channel blockers and the sulfhydryl-ACE inhibitors demonstrate protection against free-radical-mediated injury of cardiovascular cells and membranes. Rev Port Cardiol 11:1009-11
Weglicki, W B; Phillips, T M (1992) Pathobiology of magnesium deficiency: a cytokine/neurogenic inflammation hypothesis. Am J Physiol 263:R734-7

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