Abstract

The computer core will function as a general resource available to all of the projects. The consolidation of expertise in the areas of computer hardware and software, electronics, mathematics and physics will enable the core to provide information and services to all members of the group and eliminate unnecessary duplication of effort and resource. The core provides technical support and leads research projects complementing the electrophysiological studies. Technical support includes: i) providing information to investigators about the use of the hardware and software in the laboratory, ii) assistance by core engineers in software development, and iii) manipulating data for the presentation of simulation results and preparation of movies. In addition, the core will lead two research projects dedicated to the improvement of computerized models. The result of these projects is software that will be used by members of the group.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
2P01HL039707-06
Application #
3736658
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Upstate Medical University
Department
Type
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210

  Publications

Ponce-Balbuena, Daniela; Guerrero-Serna, Guadalupe; Valdivia, Carmen R et al. (2018) Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability. Circ Res 122:1501-1516
Rodrigo, M; Climent, A M; Liberos, A et al. (2017) Minimal configuration of body surface potential mapping for discrimination of left versus right dominant frequencies during atrial fibrillation. Pacing Clin Electrophysiol 40:940-946
Rodrigo, Miguel; Climent, Andreu M; Liberos, Alejandro et al. (2017) Highest dominant frequency and rotor positions are robust markers of driver location during noninvasive mapping of atrial fibrillation: A computational study. Heart Rhythm 14:1224-1233
Quintanilla, Jorge G; Pérez-Villacastín, Julián; Pérez-Castellano, Nicasio et al. (2016) Mechanistic Approaches to Detect, Target, and Ablate the Drivers of Atrial Fibrillation. Circ Arrhythm Electrophysiol 9:e002481
Takemoto, Yoshio; Ramirez, Rafael J; Yokokawa, Miki et al. (2016) Galectin-3 Regulates Atrial Fibrillation Remodeling and Predicts Catheter Ablation Outcomes. JACC Basic Transl Sci 1:143-154
Filgueiras-Rama, David; Jalife, José (2016) STRUCTURAL AND FUNCTIONAL BASES OF CARDIAC FIBRILLATION. DIFFERENCES AND SIMILARITIES BETWEEN ATRIA AND VENTRICLES. JACC Clin Electrophysiol 2:1-3
Pedrón-Torrecilla, Jorge; Rodrigo, Miguel; Climent, Andreu M et al. (2016) Noninvasive Estimation of Epicardial Dominant High-Frequency Regions During Atrial Fibrillation. J Cardiovasc Electrophysiol 27:435-42
Herron, Todd J; Rocha, Andre Monteiro Da; Campbell, Katherine F et al. (2016) Extracellular Matrix-Mediated Maturation of Human Pluripotent Stem Cell-Derived Cardiac Monolayer Structure and Electrophysiological Function. Circ Arrhythm Electrophysiol 9:e003638
Guillem, María S; Climent, Andreu M; Rodrigo, Miguel et al. (2016) Presence and stability of rotors in atrial fibrillation: evidence and therapeutic implications. Cardiovasc Res 109:480-92
Willis, B Cicero; Pandit, Sandeep V; Ponce-Balbuena, Daniela et al. (2016) Constitutive Intracellular Na+ Excess in Purkinje Cells Promotes Arrhythmogenesis at Lower Levels of Stress Than Ventricular Myocytes From Mice With Catecholaminergic Polymorphic Ventricular Tachycardia. Circulation 133:2348-59

Showing the most recent 10 out of 257 publications