Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL042443-08
Application #
5213783
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Nuzzio, Kristin M; Cullinan, David B; Novakovic, Valerie A et al. (2013) Backbone resonance assignments of the C2 domain of coagulation factor VIII. Biomol NMR Assign 7:31-4
Grant, Marianne A; Baikeev, Roustem F; Gilbert, Gary E et al. (2004) Lysine 5 and phenylalanine 9 of the factor IX omega-loop interact with phosphatidylserine in a membrane-mimetic environment. Biochemistry 43:15367-78
Phillips, J E; Lord, S T; Gilbert, G E (2004) Fibrin stimulates platelets to increase factor VIIIa binding site expression. J Thromb Haemost 2:1806-15
Li, Jianrong; Lin, Judith C; Wang, Hong et al. (2003) Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. J Neurosci 23:5816-26
Romero, Elizabeth E; Marvi, Umaima; Niman, Zachary E et al. (2003) The vitamin K-dependent gamma-glutamyl carboxylase gene contains a TATA-less promoter with a novel upstream regulatory element. Blood 102:1333-9
Gilbert, Gary E; Kaufman, Randal J; Arena, Andrew A et al. (2002) Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs. J Biol Chem 277:6374-81
Czerwiec, Eva; Begley, Gail S; Bronstein, Mila et al. (2002) Expression and characterization of recombinant vitamin K-dependent gamma-glutamyl carboxylase from an invertebrate, Conus textile. Eur J Biochem 269:6162-72
Baleja, J D (2001) Structure determination of membrane-associated proteins from nuclear magnetic resonance data. Anal Biochem 288:1-15
Falls, L A; Furie, B C; Jacobs, M et al. (2001) The omega-loop region of the human prothrombin gamma-carboxyglutamic acid domain penetrates anionic phospholipid membranes. J Biol Chem 276:23895-902
Begley, G S; Furie, B C; Czerwiec, E et al. (2000) A conserved motif within the vitamin K-dependent carboxylase gene is widely distributed across animal phyla. J Biol Chem 275:36245-9

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