Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL042444-03
Application #
3098742
Study Section
Heart, Lung, and Blood Research Review Committee A (HLBA)
Project Start
1990-04-01
Project End
1995-03-31
Budget Start
1992-04-01
Budget End
1993-03-31
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Duke University
Department
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Schwab, David E; Stamler, Jonathan S; Singel, David J (2010) EPR spectroscopy of nitrite complexes of methemoglobin. Inorg Chem 49:6330-7
Sheng, Huaxin; Yang, Wei; Fukuda, Shiro et al. (2009) Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. Free Radic Biol Med 47:917-23
Diesen, Diana L; Hess, Douglas T; Stamler, Jonathan S (2008) Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal. Circ Res 103:545-53
Granillo, Olivia M; Brahmajothi, Mulugu V; Li, Sheng et al. (2008) Pulmonary alveolar epithelial uptake of S-nitrosothiols is regulated by L-type amino acid transporter. Am J Physiol Lung Cell Mol Physiol 295:L38-43
Gutsaeva, Diana R; Carraway, Martha Sue; Suliman, Hagir B et al. (2008) Transient hypoxia stimulates mitochondrial biogenesis in brain subcortex by a neuronal nitric oxide synthase-dependent mechanism. J Neurosci 28:2015-24
Zhu, Jun; Li, Sheng; Marshall, Zermeena M et al. (2008) A cystine-cysteine shuttle mediated by xCT facilitates cellular responses to S-nitrosoalbumin. Am J Physiol Cell Physiol 294:C1012-20
Buckley, Barbara J; Li, Sheng; Whorton, A Richard (2008) Keap1 modification and nuclear accumulation in response to S-nitrosocysteine. Free Radic Biol Med 44:692-8
Reynolds, James D; Ahearn, Gregory S; Angelo, Michael et al. (2007) S-nitrosohemoglobin deficiency: a mechanism for loss of physiological activity in banked blood. Proc Natl Acad Sci U S A 104:17058-62
Nozik-Grayck, Eva; Whalen, Erin J; Stamler, Jonathan S et al. (2006) S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery. Am J Physiol Lung Cell Mol Physiol 290:L136-43
Leinenweber, Stephen B; Sheng, Huaxin; Lynch, John R et al. (2006) Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model. Eur J Pharmacol 531:126-32

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