a copy of the appropriatemonthly budget projection. The Core Administrativeoffice also councils each project leader regarding thestatus of his/her account as necessary.The Administrative Core must see that NIH and theUniversity guidelines are observed in themanagement of the program and carry out localprocedures related to travel, equipment, personnel,human and animal studies categories. Rebudgetingof equipment by project will also be reviewed firstwithin the administrative unit prior to submission toUniversity review.The Core Administrative Office makes localarrangements for consultant visits in regard toprocedures for payment of fees, travel and lodgingexpenses, reservation of seminar location,advertisement, advance procurement of specialmaterials and preparation of visit as required. TheCore Administrative Office types all program-relatedcorrespondence and manuscripts. The office alsoarranges in-house program committees and scientificmeetings by polling investigators as to the mostconvenient time and date in obtaining meetinglocations. The coordinator attends all programcommittee and seminar meetings and records,prepares and distributes the minutes. Any specialmaterials needed for these meetings are alsoprepared in advance by the project coordinator.The Administrative Core is responsible for the majorInstrumentation service 'costs. Administration Corestaff will insure that the fraction of service costsattributable to the program are accounted for andinsure that maintenance arrangements are centrallyorganized.555Mann, Kenneth G.2. Professional SkillsDr. Kenneth G. Mann is the Principal Investigator andProgram Project Grant Director. The central purposeof the Administrative Core is to coordinateinteractions between the PPG and the College ofMedicine, the University and the NIH. Additionalresponsibilities include coordination of PPG meetings,coordination of external advisor visits and preparationof progress reports. Dr. Mann will devote 5% of hisefforts to oversee proper functioning of these events.An Administrative Assistant, will require 100% of hertime to handle correspondences, progress reports,coordinating of PPG meetings, assist with manuscriptpreparation, coordinate travel arrangements for PIand Co-Pi's and external advisor visits, purchasesupplies and monitor the budgets for all projects andconsortium agreements on the PPG, includinggenerating monthly budget status reports.3. Resource UtilizationAll projects in the program project are served equallyby the above named functions

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL046703-17
Application #
7700427
Study Section
Heart, Lung, and Blood Initial Review Group (HLBP)
Project Start
Project End
Budget Start
2008-08-01
Budget End
2009-07-31
Support Year
17
Fiscal Year
2008
Total Cost
$88,012
Indirect Cost
Name
University of Vermont & St Agric College
Department
Type
DUNS #
066811191
City
Burlington
State
VT
Country
United States
Zip Code
05405
Kusak, Piotr; Czarnecka, Danuta; Gissel, Matthew et al. (2016) Activated factor IX, factor XI and tissue factor identify patients with permanent atrial fibrillation treated with warfarin who are at risk of ischemic stroke. Arch Med Sci 12:1000-1007
Bouchard, Beth A; Chapin, John; Brummel-Ziedins, Kathleen E et al. (2015) Platelets and platelet-derived factor Va confer hemostatic competence in complete factor V deficiency. Blood 125:3647-50
Brummel-Ziedins, Kathleen E; Everse, Stephen J; Mann, Kenneth G et al. (2014) Modeling thrombin generation: plasma composition based approach. J Thromb Thrombolysis 37:32-44
Bouchard, Beth A; Gissel, Matthew T; Whelihan, Matthew F et al. (2014) Platelets do not express the oxidized or reduced forms of tissue factor. Biochim Biophys Acta 1840:1188-93
de Haan, Hugoline G; Bezemer, Irene D; Vossen, Carla Y et al. (2014) Genetic variants in Cell Adhesion Molecule 1 (CADM1): a validation study of a novel endothelial cell venous thrombosis risk factor. Thromb Res 134:1186-92
Undas, A; Brummel-Ziedins, K E; Mann, K G (2014) Anticoagulant effects of statins and their clinical implications. Thromb Haemost 111:392-400
Whelihan, Matthew F; Kiankhooy, Armin; Brummel-Ziedins, Kathleen E (2014) Thrombin generation and fibrin clot formation under hypothermic conditions: an in vitro evaluation of tissue factor initiated whole blood coagulation. J Crit Care 29:24-30
Brummel-Ziedins, Kathleen E; Lam, Phillip H; Gissel, Matthew et al. (2013) Depletion of systemic concentrations of coagulation factors in blood from patients with atherosclerotic vascular disease. Coron Artery Dis 24:468-74
Young, Guy; Sorensen, Benny; Dargaud, Yesim et al. (2013) Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives. Blood 121:1944-50
Krudysz-Amblo, Jolanta; Jennings 2nd, Mark E; Knight, Tyler et al. (2013) Disulfide reduction abolishes tissue factor cofactor function. Biochim Biophys Acta 1830:3489-96

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