Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL051084-03
Application #
5214083
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Bonaventura, Celia; Henkens, Robert; Friedman, Joel et al. (2011) Steric factors moderate conformational fluidity and contribute to the high proton sensitivity of Root effect hemoglobins. Biochim Biophys Acta 1814:1261-8
Liang, Zhao-Xun; Jiang, Min; Ning, Qing et al. (2002) Dynamic docking and electron transfer between myoglobin and cytochrome b(5). J Biol Inorg Chem 7:580-8
Das, T K; Friedman, J M; Kloek, A P et al. (2000) Origin of the anomalous Fe-CO stretching mode in the CO complex of Ascaris hemoglobin. Biochemistry 39:837-42
Manjula, B N; Malavalli, A; Smith, P K et al. (2000) Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity. J Biol Chem 275:5527-34
Mueser, T C; Rogers, P H; Arnone, A (2000) Interface sliding as illustrated by the multiple quaternary structures of liganded hemoglobin. Biochemistry 39:15353-64
Juszczak, L J; Friedman, J M (1999) UV resonance raman spectra of ligand binding intermediates of sol-gel encapsulated hemoglobin. J Biol Chem 274:30357-60
Das, T K; Khan, I; Rousseau, D L et al. (1999) Temperature dependent quaternary state relaxation in sol-gel encapsulated hemoglobin. Biospectroscopy 5:S64-70
Gottfried, D S; Manjula, B N; Malavalli, A et al. (1999) Probing the diphosphoglycerate binding pocket of HbA and HbPresbyterian (beta 108Asn --> Lys). Biochemistry 38:11307-15
Hui, H L; Kavanaugh, J S; Doyle, M L et al. (1999) Structural and functional properties of human hemoglobins reassembled after synthesis in Escherichia coli. Biochemistry 38:1040-9
Huang, J; Juszczak, L J; Peterson, E S et al. (1999) The conformational and dynamic basis for ligand binding reactivity in hemoglobin Ypsilanti (beta 99 asp-->Tyr): origin of the quaternary enhancement effect. Biochemistry 38:4514-25

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