The main purpose of Core A is to provide essential administrative support for all program-related activities and to interface with the National Institutes of Health, the University of Mississippi Medical Center (UMMC) administration, the UMMC Grants and Contracts office, the Department of Physiology and other departments represented in the Program Project Grant (PPG), and the investigators of the PPG. The Program Director is responsible for the scientific and financial management of the program and will be assisted by the Co-Director. The administrative staff of Core A is responsible for purchasing and fiscal management, preparation of manuscripts and posters for national meetings, interfacing with UMMC Human Resources department on personnel issues, program-related travel by the investigators and visits by invited consultants and speakers, and reports to the National Institutes of Health. The Administrative Core also disseminates important information to the program investigators, organizes scientific meetings and seminars related to the PPG, and coordinates assessment of research progress by the Internal and External Advisory Committees. The members of the Internal Advisory Board are leaders of major academic units at UMMC and will assess progress and review the direction of the PPG on a regular basis and will help develop strong liaisons between PPG investigators and key clinical and basic science departments. The External Advisory Board consists of outstanding scientists from other institutions who have expertise that will help advance the goals of the PPG; they will provide periodic assessment of the PPG scientific progress and meet with PPG investigators and the Internal Advisory Board each year. The Administrative Core has centralized many of the day to day business and administrative operations, improving the efficiency and cost-effectiveness of the PPG.
CORE A - ADMINISTRATIVE CORE NARRATIVE Obesity and its cardiovascular and metabolic consequences, including hypertension, are major health issues affecting a large fraction of the US population. This Program Project Grant will provide new information about the underlying mechanisms by which obesity contributes to increased blood pressure and metabolic disorders in experimental models that are highly relevant to common, and difficult to treat, forms of human hypertension caused by obesity, preeclampsia, and postmenopausal hyperandrogenemia. Core A will provide essential administrative support for all program-related activities and to interface with the National Institutes of Health, the University of Mississippi Medical Center (UMMC) administration, the UMMC Grants and Contracts office, the Department of Physiology and other departments represented in the Program Project Grant (PPG), and the investigators of the PPG. The Administrative Core also disseminates important information to PPG investigators, organizes scientific meetings and seminars related to the program, and coordinates assessment of research progress by the Internal and External Advisory Committees. The Administrative Core has centralized many of the day to day business and administrative operations, improving the efficiency and cost- effectiveness of the PPG.
| Shekhar, Shashank; Cunningham, Mark W; Pabbidi, Mallikarjuna R et al. (2018) Targeting vascular inflammation in ischemic stroke: Recent developments on novel immunomodulatory approaches. Eur J Pharmacol 833:531-544 |
| Quan, Nanhu; Wang, Lin; Chen, Xu et al. (2018) Sestrin2 prevents age-related intolerance to post myocardial infarction via AMPK/PGC-1? pathway. J Mol Cell Cardiol 115:170-178 |
| Lindsey, Merry L; Mouton, Alan J; Ma, Yonggang (2018) Adding Reg3? to the acute coronary syndrome prognostic marker list. Int J Cardiol 258:24-25 |
| Brooks, Heddwen L; Lindsey, Merry L (2018) Guidelines for authors and reviewers on antibody use in physiology studies. Am J Physiol Heart Circ Physiol 314:H724-H732 |
| Aberdein, Nicola; Dambrino, Robert J; do Carmo, Jussara M et al. (2018) Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance. Am J Physiol Regul Integr Comp Physiol 314:R478-R488 |
| Eddy, Adrian C; Bidwell 3rd, Gene L; George, Eric M (2018) Pro-angiogenic therapeutics for preeclampsia. Biol Sex Differ 9:36 |
| do Carmo, Jussara M; da Silva, Alexandre A; Moak, Sydney P et al. (2018) Role of melanocortin 4 receptor in hypertension induced by chronic intermittent hypoxia. Acta Physiol (Oxf) :e13222 |
| Lindsey, Merry L; Bolli, Roberto; Canty Jr, John M et al. (2018) Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol 314:H812-H838 |
| Chen, Xu; Li, Xuan; Zhang, Wenyan et al. (2018) Activation of AMPK inhibits inflammatory response during hypoxia and reoxygenation through modulating JNK-mediated NF-?B pathway. Metabolism 83:256-270 |
| Ma, Yonggang; Mouton, Alan J; Lindsey, Merry L (2018) Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction. Transl Res 191:15-28 |
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