Abstract

?s Abstract) the Molecular Morphology and Imaging Core has been an essential component of each project of the previous PPG. The overall objective of Core B was to provide the space, facilities, supervision, and training for investigators who utilized morphological and computer analytical methodology to answer the basic questions proposed in the individual projects. Project investigators had access to core facilities to run their own experiments and were assisted by core component directors and technical staff concerning experimental design, data interpretation and technical information to best utilize facilities and instrumentation. Whereas the morphology component of Core B still maintains that original objective, the core has evolved during the past five years to meet the changing needs of the individual projects. This was accomplished by the addition of three core components whose objective includes a service function in specific, specialized areas. Each core component has a director responsible for overseeing the facilities, training, and service relative to that component.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL052813-08
Application #
6564953
Study Section
Project Start
2002-01-01
Project End
2002-12-31
Budget Start
Budget End
Support Year
8
Fiscal Year
2002
Total Cost
$194,477
Indirect Cost

  Institution

Name
Medical University of South Carolina
Department
Type
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425

  Publications

Moreno-Rodriguez, Ricardo A; Krug, Edward L; Reyes, Leticia et al. (2017) Linear array of multi-substrate tracts for simultaneous assessment of cell adhesion, migration, and differentiation. Biotechniques 63:267-274
Fresco, Victor M; Kern, Christine B; Mohammadi, Moosa et al. (2016) Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL. J Biol Chem 291:18730-9
Twal, Waleed O; Hammad, Samar M; Guffy, Sharon L et al. (2015) A novel intracellular fibulin-1D variant binds to the cytoplasmic domain of integrin beta 1 subunit. Matrix Biol 43:97-108
Zyblewski, Sinai C; Argraves, W Scott; Graham, Eric M et al. (2012) Reduction in postoperative high-density lipoprotein cholesterol levels in children undergoing the Fontan operation. Pediatr Cardiol 33:1154-9
Argraves, Kelley M; Sethi, Amar A; Gazzolo, Patrick J et al. (2011) S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease. Lipids Health Dis 10:70
Cooley, Marion A; Kern, Christine B; Fresco, Victor M et al. (2008) Fibulin-1 is required for morphogenesis of neural crest-derived structures. Dev Biol 319:336-45
Snarr, Brian S; Kern, Christine B; Wessels, Andy (2008) Origin and fate of cardiac mesenchyme. Dev Dyn 237:2804-19
Argraves, Kelley M; Gazzolo, Patrick J; Groh, Eric M et al. (2008) High density lipoprotein-associated sphingosine 1-phosphate promotes endothelial barrier function. J Biol Chem 283:25074-81
Okagawa, Hiroto; Markwald, Roger R; Sugi, Yukiko (2007) Functional BMP receptor in endocardial cells is required in atrioventricular cushion mesenchymal cell formation in chick. Dev Biol 306:179-92
Norris, Russell A; Damon, Brook; Mironov, Vladimir et al. (2007) Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues. J Cell Biochem 101:695-711

Showing the most recent 10 out of 109 publications