The function of this core unit is to evaluate the ability of the viral vectors produced by projects of this PPG to transduce human stem cells which have engraftment potential in transplantation models. This will be achieved using transplantations of transduced human hemopoietic cells into SCID/NOD mice. The unit will maintain the SCID/NOD colony and will undertake the transplantations using transduced human hemopoietic cells. The unit will undertake the immunophenotypic typing required to assess the fate of the transplanted cells and will assist the investigators in clonal cultures, in planning the experiments, and in the analysis of the results obtained.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL053750-07
Application #
6346228
Study Section
Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
7
Fiscal Year
2000
Total Cost
$223,395
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
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