Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Program Projects (P01)
Project #
5P01HL055435-02
Application #
5214394
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Dykstra, Brad; Kent, David; Bowie, Michelle et al. (2007) Long-term propagation of distinct hematopoietic differentiation programs in vivo. Cell Stem Cell 1:218-29
Bowie, Michelle B; Kent, David G; Dykstra, Brad et al. (2007) Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties. Proc Natl Acad Sci U S A 104:5878-82
Bowie, Michelle B; Kent, David G; Copley, Michael R et al. (2007) Steel factor responsiveness regulates the high self-renewal phenotype of fetal hematopoietic stem cells. Blood 109:5043-8
Dykstra, Brad; Ramunas, John; Kent, David et al. (2006) High-resolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc Natl Acad Sci U S A 103:8185-90
Olivier, Emmanuel N; Rybicki, Anne C; Bouhassira, Eric E (2006) Differentiation of human embryonic stem cells into bipotent mesenchymal stem cells. Stem Cells 24:1914-22
Peshkovsky, Alexey; Kennan, Richard P; Nagel, Ronald L et al. (2006) Sensitivity enhancement and compensation of RF penetration artifact with planar actively detunable quadrature surface coil. Magn Reson Imaging 24:81-7
Bowie, Michelle B; McKnight, Kristen D; Kent, David G et al. (2006) Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. J Clin Invest 116:2808-16
Fu, Haiqing; Wang, Lixin; Lin, Chii-Mei et al. (2006) Preventing gene silencing with human replicators. Nat Biotechnol 24:572-6
Fischer, Marlene; Schmidt, Manfred; Klingenberg, Silke et al. (2006) Short-term repopulating cells with myeloid potential in human mobilized peripheral blood do not have a side population (SP) phenotype. Blood 108:2121-3
Dykxhoorn, Derek M; Schlehuber, Lisa D; London, Irving M et al. (2006) Determinants of specific RNA interference-mediated silencing of human beta-globin alleles differing by a single nucleotide polymorphism. Proc Natl Acad Sci U S A 103:5953-8

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